The Impact of Coronavirus Disease 2019 on Pediatric Asthma in the United States

Navalpakam, Aishwarya; Pansare, Milind

doi:10.1016/j.pcl.2021.05.012

Cited by 9 publications

(12 citation statements)

References 43 publications

(38 reference statements)

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“…20,21 There is a concern that a rise in asthma exacerbations will be seen over the fall and spring this year; however, this was not noted during the first 3 waves of the pandemic. 13,[22][23][24][25][26] A study on asthma-related emergency department (ED) utilization in a high-volume U.S. children's hospital found, for the year 2020, a dramatic reduction in asthma-related ED use (compared with the prior 4 years) that was significantly below historical seasonal variation. In addition, this pattern of a dramatic reduction was observed for all levels of triage acuity.…”

Section: Impact Of Asthma On Covid-19 Outcomes In Childrenmentioning

confidence: 99%

“…[81][82][83][84][85][86] There is no evidence that these medications increase the risk of COVID-19 infection and, paradoxically, in some studies ICS therapy has been protective against severe outcomes. 26,74 Nebulization should be avoided if possible because it is aerosol generating. 41,87 Influenza vaccination is recommended.…”

Section: Asthma Managementmentioning

confidence: 99%

“…41,87 Influenza vaccination is recommended. 26 Asthma management during the pandemic must consider a more scoping approach to pediatric health. It is essential to optimize other health conditions that could have a longer-term impact on asthma symptoms and outcomes (and more broad pediatric outcomes) during this time-such as obesity.…”

Section: Asthma Managementmentioning

confidence: 99%

See 2 more Smart Citations

School Asthma Care During COVID-19: What We Have Learned and What We Are Learning

Abrams

Jordan

Szefler

2022

The Journal of Allergy and Clinical Immunology: In Practice

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Section: Impact Of Asthma On Covid-19 Outcomes In Childrenmentioning

confidence: 99%

Section: Asthma Managementmentioning

confidence: 99%

See 1 more Smart Citation

School Asthma Care During COVID-19: What We Have Learned and What We Are Learning

Abrams

Jordan

Szefler

2022

The Journal of Allergy and Clinical Immunology: In Practice

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“…[6][7][8] In the context of COVID-19, being alert and following the treatment guidelines, as well as implementing preventive measures, are of great importance for improving the outcomes among children with asthma. 9 Asthma education is one of the preventive measures. 10 The participants and the settings of asthma education vary; some sessions may include only children, 11 while some include both children and parents/guardians.…”

Section: Introductionmentioning

confidence: 99%

“…Asthma-related hospitalisation may also have an impact on educational achievements of children,4 and asthma in children is significantly associated with later risk of becoming obese,5 which is a risk factor of several chronic diseases 6–8. In the context of COVID-19, being alert and following the treatment guidelines, as well as implementing preventive measures, are of great importance for improving the outcomes among children with asthma 9. Asthma education is one of the preventive measures 10.…”

Section: Introductionmentioning

confidence: 99%

Effect of asthma education on health outcomes in children: a systematic review

Liu

Jiesisibieke²,

Tung

2022

Arch Dis Child

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BackgroundIt remains unknown whether child-oriented asthma education is associated with better health outcomes. This meta-analysis investigated the effects of asthma education on hospitalisation and emergency department and clinic visits.MethodsWe searched the Cochrane Library, PubMed and EMBASE for relevant studies from inception to 4 July 2021, and selected studies that reported hospitalisation or emergency department or clinic visits as outcomes. The participants were only children. Two authors independently selected the studies, assessed the quality of the included studies and retrieved the data. A third senior author was engaged to resolve disagreements. Fifteen longitudinal studies were included for the systematic review and meta-analysis. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 was used as the standard of reporting (PRISMA registration ID is 284509).FindingsCompared with the control group, the asthma education group had 54% lower hospitalisation risk (95% CI 0.32 to 0.66), and 31% lower emergency department visit risk (95% CI 0.59 to 0.81). Sensitivity analysis showed that the asthma education group had a reduced clinic visit risk (risk ratio (RR)=0.80, 95% CI 0.67 to 0.97). Subgroup analysis showed that asthma education involving both children and parents/guardians was associated with fewer hospitalisations (RR=0.38, 95% CI 0.24 to 0.59) and emergency department visits (RR=0.69, 95% CI 0.57 to 0.83). Asthma education in hospitals or non-hospitals can reduce the risk of hospitalisation and emergency department visits. However, only education in the hospitals was associated with the reduction of clinical visits (RR=0.45, 95% CI 0.22 to 0.92).InterpretationEducation is effective for controlling asthma, especially for reducing hospitalisation and emergency department and clinic visits. Education involving both children and parents/guardians is more effective than that involving only children. The setting of asthma education does not impact its effect to a large extent.

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The association between pre‐existing asthma and reduced risk of death among children and adolescents hospitalized with COVID‐19 in Brazil

Oliveira

Colosimo²,

Vasconcelos

et al. 2022

Pediatric Pulmonology

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Objective There have been conflicting reports on the relationship between asthma and COVID‐19 severity. This study aimed to compare the risk of death among children with asthma and healthy peers hospitalized due to COVID‐19. Methods We carried out an analysis of all pediatric patients 2–19 years of age with asthma and COVID‐19 registered in Influenza Epidemiological Surveillance Information System‐Gripe, a Brazilian nationwide surveillance database, between February 2020 and March 2022. The primary outcome was time to death, which was evaluated considering discharge as a competitive risk using the cumulative incidence function. Results Among 30,405 hospitalized children with COVID‐19, 21,340 (70.2%) had no comorbidities, 6444 (21.2%) had comorbidities other than asthma, 2165 (7.1%) had asthma, and 465 (1.5%) had asthma with other comorbidities. The estimated probability of a fatal outcome for each group was 4.1%, 14.9%, 2.1%, and 10.7%, respectively. After adjustment, children with asthma had a 60% reduction in the hazard of death than healthy peers (hazard ratio [HR] = 0.39, 95% confidence interval [CI], 0.29–0.53, p < 0.0001). Among children with asthma and no other comorbidities, two covariates were independently associated with in‐hospital mortality, age ≥12 years, HR = 4.0, 95% CI, 2.5–6.4), and low oxygen saturation at admission (HR = 2.3, 95% CI, 1.4–3.2). Conclusion Children with asthma and no comorbidities had a lower risk of death compared with healthy peers after controlling for clinical and demographic confounding factors.

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The Impact of Coronavirus Disease 2019 on Pediatric Asthma in the United States

Cited by 9 publications

References 43 publications

School Asthma Care During COVID-19: What We Have Learned and What We Are Learning

School Asthma Care During COVID-19: What We Have Learned and What We Are Learning

Effect of asthma education on health outcomes in children: a systematic review

The association between pre‐existing asthma and reduced risk of death among children and adolescents hospitalized with COVID‐19 in Brazil

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