Worldwide, oral cancer is the 15 th leading cause of death and 16 th most common malignancy. The oral cancer incidence of four per 100, 000 cases vary depending on countries, races, age, gender, and socioeconomic situations (Ferlay et al., 2019). The risk factors for oral cancer include genetic and environmental factors, and physical conditions. Discrepancies per country could be due to preventive education, culture, medical archiving conditions, and life expectancies (Wyss et al., 2013). Roughly 657, 000 new instances and 330, 000 subsequent deaths due to oral cancer have been reported worldwide each year. Betel nut chewing, excessive drinking, and smoking are health-related behaviors that could lead to heightened risk of oral cancer occurrence. Although socioeconomic status has been emphasized and linked to increased oral cancer incidence, it has also been shown that highly urbanized areas had have greater risk for cancer as well (Hung et al., 2020).Early cancer prevention and detection is a vital component in the control of cancer. Expensive and