Introduction: The long-term care in schizophrenia patients can cause care burdens, which will relate to the family's decision to do pasung. The perceived burden will be even heavier because of the COVID-19 pandemic. This review aims to identify the family care burden affecting pasung in schizophrenic patients during the COVID-19 pandemic. Methods: This scoping review was conducted by searching four databases, namely ProQuest, Science Direct, and EBSCO, and Google Scholar in the past ten years. This study uses the PRISMA 2009 protocol in filtering articles from the database. Researchers summarize based on the significance value for quantitative research, based on themes’ qualitative research, and discussed factors mentioned which may influence the family. Thus, we obtained 15 articles for final review. Results: The results obtained that the subjective burden felt by the family is a feeling of worry and sadness due to the patient's aggressive behavior and the safety of the patient, family, and environment. The objective burdens most felt by families are financial burdens, both medical costs, transportation to reach mental health services, and the cost of daily living. The COVID-19 pandemic will affect both types of care burdens, thereby affecting the quality of care for families with schizophrenia patients in pasung. Conclusion: Schizophrenia patients are one of the populations that are vulnerable to COVID-19. Nurse plays a role in the ability to overcome the burden of schizophrenia care and improve adaptation to the current pandemic to create optimal mental health in the community.