The impact of covid-19 on thyroid function tests in pregnancy

Atalay, Altay; Besimoğlu, Berhan; Sınacı, Selcan; Kaya, Ecem; Özkavak, Onur; Öcal, Fatma Doğa; Özgü-Erdinç, A. Seval; Şahın, Dilek

doi:10.1007/s12020-022-03248-9

Cited by 3 publications

(4 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While no statistically significant correlation was found between CRP values in the groups under investigation, it was observed that a significant correlation existed between CRP and TSH values in the hypothyroidism group (p=0.007). This finding aligns with data presented in a study by Atalay et al, which reported a significant negative relationship between CRP levels and FT3 and TSH levels (p < 0.001, p = 0.005) [11].…”

Section: Figure 2: the Distribution Of Fetal Weight In The Two Groups...supporting

confidence: 93%

“…Autoimmune thyroiditis with hypothyroidism has a prevalence of 2-3% during pregnancy [10]. A study conducted by Atalay et al in 2023, investigating the effect of COVID-19 on thyroid function tests and considering that the severity of SARS-CoV-2 infection amplifies perinatal complications, proposed that free triiodothyronine (FT3) levels are associated with the severity of the viral infection [11].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

SARS-CoV-2 Infection in Pregnant Women With Hypothyroidism

Iordache,

Meca,

Cirstoiu

2024

Cureus

View full text Add to dashboard Cite

BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been linked to increased maternal and fetal morbidity and mortality, as evidenced by numerous studies. Given the potential exacerbation of autoimmune diseases during viral infections, maternal and fetal complications such as preterm birth, low birth weight, or preeclampsia, often observed in pregnancies involving autoimmune thyroiditis with hypothyroidism, may be further aggravated. This study seeks to ascertain whether the association between viral infection and hypothyroidism contributes to an increase in adverse pregnancy outcomes. MethodsThis study included a cohort of 145 pregnant women with SARS-CoV-2 infection, who delivered in the

show abstract

Section: Figure 2: the Distribution Of Fetal Weight In The Two Groups...supporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

SARS-CoV-2 Infection in Pregnant Women With Hypothyroidism

Iordache,

Meca,

Cirstoiu

2024

Cureus

View full text Add to dashboard Cite

show abstract

“…In this context, other laboratory tests may aid to identify and isolate suspected patients early and may predict severity until nucleic acid test results are available. Studies show that several clinical and laboratory parameters help in diagnosis, grading the severity of the disease, and prognosis 7–10 . The most commonly studied parameter is complete blood count (CBC), which is the easiest to perform in all facilities and is part of the basic examination of pregnant women at all levels, from primary care facilities to tertiary care hospitals 11 …”

Section: Introductionmentioning

confidence: 99%

“…Studies show that several clinical and laboratory parameters help in diagnosis, grading the severity of the disease, and prognosis. [7][8][9][10] The most commonly studied parameter is complete blood count (CBC), which is the easiest to perform in all facilities and is part of the basic examination of pregnant women at all levels, from primary care facilities to tertiary care hospitals. 11 White blood cells (WBCs) are routinely measured in pregnancy to investigate infections or inflammation, and it has been reported that total WBC count is elevated in pregnancy, while eosinophil counts remain unchanged and are approximately the same as values for nonpregnant women.…”

Section: Introductionmentioning

confidence: 99%

The role of eosinophil as a diagnostic, differential, and prognostic marker for Covid‐19 during pregnancy: Case–control study from tertiary center

Atalay

Sınacı

Besimoğlu

et al. 2023

J of Obstet and Gynaecol

Self Cite

View full text Add to dashboard Cite

Purpose To evaluate the level of eosinophil count in Covid‐19 pregnant patients as a cost‐effective tool for aiding in diagnosis, differential diagnosis, and prognosis and, to assess whether eosinopenia could be similar or superior to lymphopenia in pregnancy with Covid‐19. Methods Retrospective case–control study was conducted including pregnant women tested simultaneously for SARS‐CoV‐2 by RT‐PCR and complete blood count (CBC). Eosinophil counts (EOS), lymphocytes (LYM), neutrophils (NEU) with calculation of EOS/LYM ratio, EOS/NEU ratio, NEU/LYM ratio, LYM/NEU ratio (LNR), eosinopenia, and lymphopenia were compared between the groups. ROC analysis was performed for determination of optimal cut‐off values and comparative analysis between AUC were performed using the paired sample design. Logistic regression was used to determine the factors affecting the categorical variables. Results Four thousand two hundred sixteen pregnant women were included in the final analysis of which (n = 845) as healthy control group, (n = 1482) as non Covid‐19 patient group and (n = 1889) as Covid‐19 group. Covid‐19 group was divided into three subgroups based on severity. To diagnose and distinguish Covid‐19 from other infectious conditions, EOS had better performance with higher area under curve (AUC) (0.769 and 0.757 AUC, respectively, p < 0.001). Categorically, eosinopenia had better diagnostic (Covid‐19 vs. healthy), prognostic (severe–critical vs. mild–moderate), and differential diagnostic (Covid‐19 vs. non Covid‐19) performance than lymphopenia (OR = 5.5 vs. 3.4, OR = 3.4 vs. 1.8, OR = 5.4 vs. 2.7 p = 0.000). Conclusion Eosinopenia is a low‐cost, reliable, and convenient marker for Covid‐19 not only in diagnosis, but also in prognosis by acting as an early marker for predicting severe–critical cases.

show abstract