The Impact of Developmental Behavioral Pediatrics in a Population of Children with Down Syndrome

Shaw, Daphna; Bar, Sari; Champion, Jane Dimmitt

doi:10.1016/j.pedn.2020.10.019

Cited by 10 publications

(9 citation statements)

References 19 publications

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“…Severe somatic disease may be directly linked to both development of cataract and presence of mental disease [14][15][16][17][18][19][20] . We found a doubling of the risk of unspecific developmental delay disorder in children with cataract also in analyses adjusting for diseases with known neuro-developmental comorbidity and diseases in which the treatment involves potential adverse neuro-developmental exposures 33,34,[37][38][39] .…”

Section: Dicussionmentioning

confidence: 99%

“…Visually disturbing cataracts can be removed by surgery 10 but prolonged and intensive visual and optical rehabilitation is required 11,12 . Childhood cataract can occur isolated or can be seen in combination with somatic comorbidities 13 that may be associated with neurodevelopmental disorders [14][15][16][17][18][19][20] . Most cases of childhood cataract occur in early childhood 21 , which is also the period of onset of several childhood mental disorders, in particular neurodevelopmental disorders 22 .…”

Section: Introductionmentioning

confidence: 99%

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Increased Incidence of Mental Disorders in Children with Cataract: Findings from a Population-based Study

Al‐Bakri¹,

Skovgaard

Bach‐Holm

et al. 2022

American Journal of Ophthalmology

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Section: Dicussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Increased Incidence of Mental Disorders in Children with Cataract: Findings from a Population-based Study

Al‐Bakri¹,

Skovgaard

Bach‐Holm

et al. 2022

American Journal of Ophthalmology

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“…They found that reduction in the percentage of REM sleep and the presence of OSA were associated with impaired language function in patients with DS 18 . Other studies with similar designs have correlated a reduction in slow-wave sleep with poorer performance in verbal learning and executive functions in patients with DS [26][27][28][29][30] .…”

Section: Sleep Disordered Breathing In Patients With Down Syndrome An...mentioning

confidence: 99%

Sleep disorders in Down syndrome: a systematic review

Santos¹,

Costa²,

Linhares

et al. 2022

Arq. Neuro-Psiquiatr.

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Background: Sleep disorders are commonly observed in children with Down syndrome (DS) and can lead to significant behavioral and cognitive morbidities in these individuals. Objective: To perform a systematic review evaluating sleep disorders in individuals with DS. Methods: Search strategies were based on combinations of keywords: “Down syndrome”; “trisomy 21”; “sleep disorders”; “dyssomnias”; “sleep apnea”; “obstructive”; “sleeplessness”; “insomnia”; “parasomnias”; and “excessive daytime sleepiness”. PubMed and Science Direct were used. Only original studies and retrospective reviews in English published between January 2011 and March 2021 were included. Results: 52 articles were included, most of them involving children and adolescents under 18 years of age. The main sleep disorder associated with DS was obstructive sleep apnea (OSA). Some studies reported the presence of cognitive dysfunction in patients with DS and sleep-disordered breathing, and few have been found about parasomnia, insomnia, and daytime sleepiness in these patients. Movement disorders and unusual postures during sleep may be related to disordered sleep breathing in DS. The main treatment options for OSA are continuous positive airway pressure therapy (CPAP), surgery, and weight control. Computational modeling associated with MRI has been used to plan surgical interventions in these patients. Conclusions: Individuals with DS are at high risk of developing sleep-related breathing disorders. The main sleep disorder associated with DS was OSA. The presence of sleep-disordered breathing contributes to a worsening of cognitive function in patients with DS.

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“…30 Neurocognitive impairments may explain why they are more prone to developing hyperactivity, impulsivity, anxiety, and tantrums when compared with the general population. 48 They are also predisposed to autism spectrum disorder and attentiondeficit/hyperactivity disorder. 48 Hearing difficulties and language delay deficits also contribute to communication barriers in this population.…”

Section: Neurologicalmentioning

confidence: 99%

Down Syndrome: A Review of Key Perioperative Implications

Hines¹,

Simmons²

2022

AORN Journal

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Down syndrome (DS) is the most common chromosomal abnormality in humans that is compatible with life. This syndrome occurs when there is an extra copy of the 21st chromosome. Down syndrome is associated with numerous comorbidities that can pose challenges for the perioperative nurse caring for a patient with DS undergoing surgery. These challenges can affect the patient assessment, communication with the patient, and patient safety (eg, preventing complications). As the life expectancy of people with DS has increased, so too have the chances that perioperative nurses will care for a patient with this disorder. This article reviews the pathophysiology of DS, discusses common comorbidities that may directly affect perioperative care, and reviews an exemplar case study that demonstrates how personnel with knowledge of DS can positively influence surgical team decision making for these patients in the perioperative setting.

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The Impact of Developmental Behavioral Pediatrics in a Population of Children with Down Syndrome

Cited by 10 publications

References 19 publications

Increased Incidence of Mental Disorders in Children with Cataract: Findings from a Population-based Study

Increased Incidence of Mental Disorders in Children with Cataract: Findings from a Population-based Study

Sleep disorders in Down syndrome: a systematic review

Down Syndrome: A Review of Key Perioperative Implications

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