2020
DOI: 10.1097/tp.0000000000003262
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The Impact of Donor Asphyxiation or Drowning on Pediatric Lung Transplant Recipients

Abstract: Background. Donors with drowning or asphyxiation (DA) as a mechanism of death (MOD) are considered high risk in pediatric lung transplantation. We sought to evaluate whether recipients of DA donors had negatively impacted outcomes. Methods. Pediatric recipients recorded in the United Network for Organ Sharing registry between 2000 and 2019 were included. Primary stratification was donor MOD. Propensity matching with a 1:1 ratio was performed to balance … Show more

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Cited by 4 publications
(6 citation statements)
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“…Outcomes were summarized in Table S12 (SDC, http://links.lww.com/TP/C527). 12-23 Heart and liver transplantation were addressed by single studies only. No published studies addressed outcomes for recipients of a pancreas or simultaneous kidney pancreas.…”
Section: Resultsmentioning
confidence: 99%
See 3 more Smart Citations
“…Outcomes were summarized in Table S12 (SDC, http://links.lww.com/TP/C527). 12-23 Heart and liver transplantation were addressed by single studies only. No published studies addressed outcomes for recipients of a pancreas or simultaneous kidney pancreas.…”
Section: Resultsmentioning
confidence: 99%
“…Interestingly, this was in contrast to the published literature investigating the impact of donor death by ligature asphyxiation on lung transplant outcomes. [12][13][14][15][16][17][18][19][20][21] There is little information in the literature concerning the outcome following transplantation of lungs, hearts, or livers from either DBD or DCD donors who died following ligature asphyxiation, with the majority of published work being single-center case studies/series. A major strength of the present registry analysis is that it provides the first comprehensive analysis of transplant outcomes in recipients of hearts, lungs, livers‚ and pancreases from donors who died following ligature asphyxiation across different transplant centers.…”
Section: Discussionmentioning
confidence: 99%
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“…16 However, recent publications have shown that primary graft function and longterm recipient survival may be equal to those of organs from nonasphyxiated donors, even for high-risk organs such as the lung. [17][18][19][20][21] Donor lungs procured from asphyxiated victims often show signs of damage due to barotrauma and edema. 19 The lungs of avalanche victims may be additionally damaged by external thoracic compression and by negativepressure lung injury caused by airway obstruction.…”
Section: Discussionmentioning
confidence: 99%