The Impact of Dopamine on Hemodynamics, Oxygen Metabolism, and Cerebral Resuscitation After Restoration of Spontaneous Circulation in Pigs

Liu, Zhaoxia; Li, Chunsheng; Wu, Jing; Wu, Caijun

doi:10.1016/j.jemermed.2009.08.049

Cited by 3 publications

(2 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our results indicate that additional studies assessing the short-and long-term evolution of these parameters as well as the effectiveness of drugs that could improve myocardial contractility in this period are needed [15,16]. Femoral arterial thermodilution measurement has been used in infantile animal models and in children [17][18][19][20][21][22][23][24]; it has showed an acceptable correlation with pulmonary arterial thermodilution by using a Swan-Ganz catheter [19,23], and therefore it might be a reliable and less invasive hemodynamic monitoring tool in the post-CA period in children.…”

Section: Cardiovascular Parametersmentioning

confidence: 95%

Hemodynamic, respiratory, and perfusion parameters during asphyxia, resuscitation, and post-resuscitation in a pediatric model of cardiac arrest

et al. 2010

View full text Add to dashboard Cite

show abstract

Section: Cardiovascular Parametersmentioning

confidence: 95%

Hemodynamic, respiratory, and perfusion parameters during asphyxia, resuscitation, and post-resuscitation in a pediatric model of cardiac arrest

et al. 2010

View full text Add to dashboard Cite

show abstract

“…First, we were unable to stratify the types of CPR interventions due to the heterogeneity of CPR interventions (including defibrillation, anti-arrhythmic drugs, adrenergic drugs, and mechanical CPR). Efforts were made to provide specific information in each article in Supplementary Material B [40–256] to identify the type of VF induction used in the experiment of interest. Second, the quality of the included studies was not assessed.…”

Section: Discussionmentioning

confidence: 99%

Systematic review of swine models for ventricular fibrillation induction in evaluating cardiopulmonary resuscitation methods

Low,

Azahar,

Samson

et al. 2024

Cardiology Plus

View full text Add to dashboard Cite

Background and purpose: Ventricular fibrillation (VF) has been studied using a variety of swine models, historically balloon occlusion of the coronary artery and asphyxiation, and more recently, percutaneous electrical induction. These methods differ in face and construct validity, as well as requirement for expertise, cost, and duration. This study aimed to provide a systematic review these methods and their selection in research. Methods: Electronic searches were conducted in PubMed, Scopus, and Google Scholar. The Utstein-Style Guidelines for Uniform Reporting of Laboratory cardiopulmonary resuscitation (CPR) research were used to identify the extracted variables by two independent investigators. Discrepancy was resolved by discussion with the third investigator. Results: We included 236 studies published from 1990 to 2024. The most commonly used method was electrical induction using a pacing wire cannulated through the external jugular vein into the right ventricle (n = 112), followed by transthoracic electrical induction (n = 28), asphyxiation (n = 20), electrical induction via two subcutaneous needles (n = 15), and balloon occlusion (n = 10). The mean and standard deviation (SD) of the untreated VF duration were 6.9 and 5.0 minutes, respectively. Female and male pigs were used exclusively in 52 and 45 studies, respectively; both sexes were used in 31 studies; 106 studies not reporting the sex. The mean weight of the pigs was 30.2 ± 12.4 kg in 209 studies, and the number of pigs used in the studies ranged from 2 to 271 with a median of 20 (interquartile range: 15–30) pigs in 223 studies. The four most commonly used drugs for anesthesia/preparation were ketamine (n = 145), propofol (n = 76), isoflurane (n = 68), and pentobarbital (n = 61), either alone or in combination. Higher current and voltage were used for less invasive methods. Conclusions: The two most common electric method to induce VF were invasive pacing at the right ventricle and non-invasive transthoracic electrical induction. Asphyxiation was the most common ischemic VF induction. The choice of the VF induction method depends on cost, expertise, feasibility, and the nature of the CPR intervention to be tested.

show abstract

Transtracheal ventilation with a novel ejector-based device (Ventrain) in open, partly obstructed, or totally closed upper airways in pigs

Paxian

Preussler

Reinz

et al. 2015

British Journal of Anaesthesia

View full text Add to dashboard Cite

The results of this study suggest that the Ventrain device can ensure sufficient oxygenation and ventilation through a small-bore transtracheal catheter when the airway is open, partly obstructed, or completely closed. Minute ventilation and avoidance of high airway pressures were superior in comparison with traditional hand-triggered jet ventilation, particularly in the event of complete upper airway obstruction.

show abstract

The Impact of Dopamine on Hemodynamics, Oxygen Metabolism, and Cerebral Resuscitation After Restoration of Spontaneous Circulation in Pigs

Cited by 3 publications

References 17 publications

Hemodynamic, respiratory, and perfusion parameters during asphyxia, resuscitation, and post-resuscitation in a pediatric model of cardiac arrest

Hemodynamic, respiratory, and perfusion parameters during asphyxia, resuscitation, and post-resuscitation in a pediatric model of cardiac arrest

Systematic review of swine models for ventricular fibrillation induction in evaluating cardiopulmonary resuscitation methods

Transtracheal ventilation with a novel ejector-based device (Ventrain) in open, partly obstructed, or totally closed upper airways in pigs

Contact Info

Product

Resources

About