Introduction: Endometriosis is a chronic inflammatory condition affecting 6 to 10% of the women at reproductive age. The clinical manifestations of this condition differ according to its location. Case Presentation: In this study, the case of a 30-year-old infertile woman presented with a history of abdominal pain and three times cleavage formation arrests after Intracytoplasmic sperm injection (ICSI) was reported. Ethanol sclerotherapy (EST) was selected due to abdominal pain and previous in vitro fertilization (IVF) cycles, and ovarian stimulation was initiated eight weeks later. The patient was stimulated in a minimal stimulation protocol. A total of six oocytes were retrieved, resulting in 3 embryos of good to moderate quality that were frozen. The patient became pregnant following two embryo transfers in the FET cycle. Conclusion: EST may have been considered as a first-line therapy to treat infertility after the failure of IVF. It was found that EST may have improved IVF outcomes.