The Impact of Functional Bars and Adapted Physical Activity on Quality of Life in Chronic Kidney Disease: A Pilot Study

Abstract

Chronic kidney disease (CKD) represents a public health problem because it is characterized by several comorbidities, including uremic sarcopenia (US), and a poor quality of life. Currently, there are no standardized treatments available to counteract the onset of US but only some possible therapeutic approaches to slow its progression. The aim of this pilot study is to collect descriptive data in order to design a clinical trial based on the power analysis and simple size. The purpose of this pilot study was to evaluate the possible beneficial action induced by the functional anti-inflammatory and antioxidant bars in combination with the adapted physical activity (APA), on the onset and progression of US and other related-CKD comorbidities. We enrolled 21 CKD patients under conservative therapy, divided into four groups: (A) the physical exercise program (PEP), three times a week, in combination with the daily consumption of the two functional bars group; (B) the PEP group; (C) the daily consumption of the two functional bars group; (D) the control group. The duration of the study protocol was 12 weeks. We observed an improvement trend of body composition, blood pressure levels, lipid metabolism, and functional test in A and B groups. These preliminary data would seem to confirm the effectiveness of APA and to demonstrate the additive role of the natural bioactive compound’s assumption in countering US and other CKD comorbidities.

Lifestyle Interventions, Kidney Disease Progression, and Quality of Life: A Systematic Review and Meta-analysis

“…The characteristics of the included studies are outlined in Table 2 , Table 3 , Table 4 , Table 5 . 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 ,…”

“…Dietary interventions were investigated in 24 studies, 46 , 47 , 48 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 with exercise interventions used in 23 studies. 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 Eleven studies assessed interventions involving multiple components (eg, both diet and exercise), 16 , 82 , 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , ...…”

Effect of Online Home-Based Training on Functional Capacity and Strength in Two CKD Patients: A Case Study

“…The obtained results suggest the possible beneficial role of the online PA program for this patient population, and this hypothesis is more corroborated by the results obtained in Patient B, who increased the SMMI. For this reason, in our clinical trial ongoing, we are collecting body composition parameters such as FM and FFM through bioimpedance analysis, to better investigate the impact of PA on body composition changes in CKD patients [ 56 ]. CKD is associated with an increased OS and it has also been described by several authors as a progression factor to ESRD [ 57 , 58 , 59 ], representing a nontraditional risk factor for all-cause mortality in this population [ 46 ].…”

The Effectiveness of Wearable Devices in Non-Communicable Diseases to Manage Physical Activity and Nutrition: Where We Are?

“…The emerging literature contains many examples of interventions, in which physical activity and nutrition are part of the same model, some of which are applied to populations living with NCDs, and the results demonstrate that this can be a model to scale up [ 97 , 98 , 99 ]. The success and feasibility of introducing this new model of care, which complements standard care, requires the implementation of specific action plans that may differ from country to country.…”