Digital literacy is critical in the current era of digitalization. Therefore, students are required to be digitally literate. This study aims to improve students’ digital literacy using an android-based e-module in chemical bonding. This study used a quasi-experimental method with a pre-experimental design that included a pretest and posttest for one group. For this study, 70 preservice teachers (10 males and 60 females) from the Department of Chemistry Education at a private university in Indonesia were recruited. The Digital Literacy Questionnaire (DLQ) was used to measure students’ digital literacy. To analyze the data, we used paired t-tests and N-gain. The results indicated a significant increase in digital literacy scores before and after treatment. Thus, it can be concluded that using an android-based e-module significantly enhances students’ digital literacy on chemical bonds. Due to its effectiveness, we recommend teachers use this e-module to elevate students’ academic performance, in general, in chemistry.