The impact of housing environment color on zebrafish anxiety-like behavioral and physiological (cortisol) responses

Abreu, Murilo S. de; Giacomini, Ana C.V.V.; Genário, Rafael; Santos, Bruna E. dos; Marcon, Leticia; Demin, Konstantin A.; Kalueff, Allan V.

doi:10.1016/j.ygcen.2020.113499

Cited by 24 publications

(21 citation statements)

References 39 publications

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“…Different numbers of animals per group or replicates have also been used in other studies. [23][24][25][26] The method used for the whole body extraction of cortisol was based on Cachat et al. 22 Frozen zebrafish samples from behavior testing were thawed and allowed to attain room temperature.…”

Section: Measurement Of Cortisol Concentrationmentioning

confidence: 99%

Perturbations in Amino Acid Metabolism in Reserpine-Treated Zebrafish Brain Detected by¹H Nuclear Magnetic Resonance-Based Metabolomics

et al. 2021

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Depression is a complex and disabling psychiatric disorder, which is expected to be a leading cause for disability by 2030. According to World Health Organization, about 350 million people are suffering with mental health disorders around the globe, especially depression. However, the mechanisms involved in stress-induced depression have not been fully elucidated. In this study, a stress-like state was pharmacologically induced in zebrafish using reserpine, a drug widely used to mediate depression in experimental animal models. Zebrafish received single intraperitoneal (i.p.) injections of 20, 40, and 80 mg/kg body weight reserpine doses and were subjected to open-field test at 2, 24, 48, 72, and 96 h after the treatment. Along with observed changes in behavior and measurement of cortisol levels, the fish were further examined for perturbations in their brain metabolites by 1 H nuclear magnetic resonance (NMR)-based metabolomics. We found a significant increase in freezing duration, whereas total distance travelled was decreased 24 h after single intraperitoneal injection of reserpine. Cortisol level was also found to be higher after 48 h of reserpine treatment. The 1 H NMR data showed that the levels of metabolites such as glutamate, glutamine, histamine, valine, leucine and histidine, lactate, l-fucose, betaine and c-amino butyric acid (GABA), b-hydroxyisovalerate, and glutathione were significantly decreased in the reserpine-treated group. This study provided some insights into the molecular nature of stress that could contribute toward a better understanding of depression disorder.

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Section: Measurement Of Cortisol Concentrationmentioning

confidence: 99%

Perturbations in Amino Acid Metabolism in Reserpine-Treated Zebrafish Brain Detected by¹H Nuclear Magnetic Resonance-Based Metabolomics

et al. 2021

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“…Larvae in blue, yellow and red tanks had lower growth rates, although highest survival rate was observed in the red tanks, closely followed by those in white, blue, yellow and grey tanks. Probably, with increased age and experience the larvae in different tanks were able to adapt to their colour environments and adjusted their feeding strategy or behavioural responses, which was crucial for their survival and growth (de Abreu et al, 2020; Ferosekhan et al, 2020). This is the first study to report a higher survival rate of snubnose pompano larvae in red tanks.…”

Section: Discussionmentioning

confidence: 99%

“…Tank colour affects survival and growth performance (Bera et al, 2019; Ferosekhan et al, 2020; Pedreira & Sipaúba‐Tavares, 2001; Sebesta et al, 2019; Tamazouzt et al, 2000). It also affects physiological processes and behavioural responses, such as feeding (Bera et al, 2019; El‐Sayed & El‐Ghobashy, 2011; Wang et al, 2016), digestion (Rungruangsak‐Torrissen et al, 2006; Santisathitkul et al, 2020), body composition (Banan et al, 2011; Papoutsoglou et al, 2000), reproduction (Volpato et al, 2004), skin pigmentation (Eslamloo et al, 2015; Yasir & Qin, 2009) and stress response of fish larvae and juveniles (Banan et al, 2013; de Abreu et al, 2020; Sopinka et al, 2016; Wang et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

“…Despite its importance in the successful management of fish larvae, there are only a few studies on the effects of tank colour on physiological responses and other attributes, such as body composition, digestives enzyme activities and cortisol levels in marine fish (de Abreu et al, 2020; Banan et al, 2011; McLean et al, 2008; Papoutsoglou et al, 2000; Rungruangsak‐Torrissen et al, 2006; Santisathitkul et al, 2020). The impact of tank colour on such characteristics at different larval stages of snubnose pompano under captivity is still unknown.…”

Section: Introductionmentioning

confidence: 99%

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Effect of tank colour on growth, survival, stress level, digestive enzymatic activities and body composition of snubnose pompano ( Trachinotus blochii Lacépède) larvae

et al. 2021

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Snubnose pompano (Trachinotus blochii, Lacépède) is a commercially important fish species that shows robust growth in captive environment. Tank colour is an important factor affecting the growth of fish larvae in aquaculture. Although the effect of tank colour has been studied in several fish species, it has not been studied in the snubnose pompano. We aimed to investigate how tank colour affects overall growth, survival, body composition, stress levels and digestive enzyme activities of snubnose pompano larvae at early larval stage and late larval stage. We noted that early–larval–stage larvae showed higher growth, crude protein contents and lower digestive enzyme activities when reared in blue and white tanks. Larvae showed low‐stress levels when reared in grey and blue tanks. The same larvae showed low‐survival and high‐stress levels when reared in red tanks. The late–larval–stage larvae showed high growth and lipids, and low‐digestive enzymes activities in white and yellow tanks. The larvae showed high‐stress levels and low‐ash contents when reared in red tanks. These differences are most likely due to the differences in light intensity inside tanks, which affects the ability of larvae to find and catch prey. Overall, our study sheds new light on cultivation conditions for snubnose pompano larvae. We recommend blue tanks for growing early–larval–stage larvae and white or yellow tanks for late‐larval‐stage larvae.

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“…Stress plays a key role in the states of various diseases such as hypertension, diabetes, peptic ulcer, immuno-suppression, anxiety reproductive dysfunctions, central nervous system (CNS), metabolic system, and endocrine system [ 38 , 39 ]. With regard to the above, stress has been associated with mood, cognition, schizophrenia, and other psychiatric disorders [ 40 , 41 ]. According to the Global Organization for Stress, in approximately 77% of individuals who are stressed, their condition impacts on their physical health.…”

Section: Biological and Pharmaceutical Properties Of Sceletium Spmentioning

confidence: 99%

A Chewable Cure “Kanna”: Biological and Pharmaceutical Properties of Sceletium tortuosum

et al. 2021

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Sceletium tortuosum (L.) N.E.Br. (Mesembryanthemaceae), commonly known as kanna or kougoed, is an effective indigenous medicinal plant in South Africa, specifically to the native San and Khoikhoi tribes. Today, the plant has gained strong global attraction and reputation due to its capabilities to promote a sense of well-being by relieving stress with calming effects. Historically, the plant was used by native San hunter-gatherers and Khoi people to quench their thirst, fight fatigue and for healing, social, and spiritual purposes. Various studies have revealed that extracts of the plant have numerous biological properties and isolated alkaloids of Sceletium tortuosum are currently being used as dietary supplements for medicinal purposes and food. Furthermore, current research has focused on the commercialization of the plant because of its treatment in clinical anxiety and depression, psychological and psychiatric disorders, improving mood, promoting relaxation and happiness. In addition, several studies have focused on the isolation and characterization of various beneficial bioactive compounds including alkaloids from the Sceletium tortuosum plant. Sceletium was reviewed more than a decade ago and new evidence has been published since 2008, substantiating an update on this South African botanical asset. Thus, this review provides an extensive overview of the biological and pharmaceutical properties of Sceletium tortuosum as well as the bioactive compounds with an emphasis on antimicrobial, anti-inflammatory, anti-oxidant, antidepressant, anxiolytic, and other significant biological effects. There is a need to critically evaluate the bioactivities and responsible bioactive compounds, which might assist in reinforcing and confirming the significant role of kanna in the promotion of healthy well-being in these stressful times.

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The impact of housing environment color on zebrafish anxiety-like behavioral and physiological (cortisol) responses

Cited by 24 publications

References 39 publications

Perturbations in Amino Acid Metabolism in Reserpine-Treated Zebrafish Brain Detected by¹H Nuclear Magnetic Resonance-Based Metabolomics

Perturbations in Amino Acid Metabolism in Reserpine-Treated Zebrafish Brain Detected by¹H Nuclear Magnetic Resonance-Based Metabolomics

Effect of tank colour on growth, survival, stress level, digestive enzymatic activities and body composition of snubnose pompano ( Trachinotus blochii Lacépède) larvae

A Chewable Cure “Kanna”: Biological and Pharmaceutical Properties of Sceletium tortuosum

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The impact of housing environment color on zebrafish anxiety-like behavioral and physiological (cortisol) responses

Cited by 24 publications

References 39 publications

Perturbations in Amino Acid Metabolism in Reserpine-Treated Zebrafish Brain Detected by1H Nuclear Magnetic Resonance-Based Metabolomics

Perturbations in Amino Acid Metabolism in Reserpine-Treated Zebrafish Brain Detected by1H Nuclear Magnetic Resonance-Based Metabolomics

Effect of tank colour on growth, survival, stress level, digestive enzymatic activities and body composition of snubnose pompano ( Trachinotus blochii Lacépède) larvae

A Chewable Cure “Kanna”: Biological and Pharmaceutical Properties of Sceletium tortuosum

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Product

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Perturbations in Amino Acid Metabolism in Reserpine-Treated Zebrafish Brain Detected by¹H Nuclear Magnetic Resonance-Based Metabolomics

Perturbations in Amino Acid Metabolism in Reserpine-Treated Zebrafish Brain Detected by¹H Nuclear Magnetic Resonance-Based Metabolomics