The impact of HPMC structure in the modulation of in vitro lipolysis: The role of bile salts

New hydrocolloid‐based emulsions for replacing fat in panna cottas: a structural and sensory study

“…This could explain why the MC panna cottas (P75M and P100M) were firmer than those prepared with the HPMC emulsion (P75H and P100H). It is well known that self‐assembly of cellulose ethers is driven by hydrophobic interactions between the hydrophobic substituents (methyl groups) . The higher the methyl substitution, the stronger are the hydrophobic interactions, so stronger consistencies are obtained.…”

“…It is well known that self-assembly of cellulose ethers is driven by hydrophobic interactions between the hydrophobic substituents (methyl groups). 31 The higher the methyl substitution, the stronger are the hydrophobic interactions, so stronger consistencies are obtained. Therefore, in the case of HPMC, the lower methyl group content and the presence of the more polar and larger hydroxypropyl groups that inhibit intermolecular association lead to the formation of a weaker consistency system than with MC.…”

Oil-in-water emulsions stabilised by cellulose ethers: stability, structure and in vitro digestion

“…In recent studies, the effect of different hydroxypropyl methylcelluloses (HPMCs) on lipid digestion of o/w emulsions has been investigated. 2,16 Torcello-Gómez and Foster 2 found similar results of lipolysis curves regardless the molecular weight, substitution pattern or initial concentration in the bulk of the HPMCs. However, Pizones Ruiz-Henestrosa et al 16 attributed the slight difference in lipolysis extent between two types of HPMC to the molecular events occurring at the interface upon bile salts adsorption, due to their different methyl/hydroxyl ratio.…”

“…2,16 Torcello-Gómez and Foster 2 found similar results of lipolysis curves regardless the molecular weight, substitution pattern or initial concentration in the bulk of the HPMCs. However, Pizones Ruiz-Henestrosa et al 16 attributed the slight difference in lipolysis extent between two types of HPMC to the molecular events occurring at the interface upon bile salts adsorption, due to their different methyl/hydroxyl ratio. Therefore, there is no a clear trend on the lipid digestion and its relation to the molecular weight or degree and type of substitution of the cellulose ethers used as emulsifiers in o/w emulsions and thus further investigation is needed.…”

Functional and Engineered Colloids from Edible Materials for Emerging Applications in Designing the Food of the Future

“…Recent studies have also reported on the effect of adjuvant bulk phase components on delaying lipolysis. For instance, cellulose‐based components such as cellulose ethers (dietary fiber) and nanocellulose may alter the process of lipid digestion and absorption through one or more of following mechanisms: nonspecific binding with fatty acids, bile salts or digestive enzymes; forming a protective barrier against the action of bile salts and lipase; and disruption of mixed micelles of digested lipids and bile salts which reduces transport into the mucosal surface barrier . Attempts made by Gomez and Foster to unravel the mode of interactions between commercial cellulose ethers and bile salts using thermal analysis, revealed that substitution type/pattern of cellulose ethers influenced their interaction with bile salts .…”