The Impact of Idiopathic Generalized Epilepsy on Executive Functions

Koganti, Haritha; Sundaramurthy, Harsha; Sc, Nemichandra; Kashyap, Rithvik S; Joshi, Siddharth; Colaco, Vimala

doi:10.1177/0972753120968751

Cited by 5 publications

(2 citation statements)

References 11 publications

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“…Koganti and his colleagues found problems in planning (Tower of London), verbal fluency (verbal n-back, category fluency, and word fluency), and inhibition (Stroop test) in 75 idiopathic generalized epilepsy adults [23].…”

Section: Comparison To Previous Studiesmentioning

confidence: 99%

The ability of executive functions to predict deterioration in social abstraction in adolescents with idiopathic generalized epilepsy

Hadad

Ibrahim

Desoky

et al. 2022

Middle East Curr Psychiatry

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Background Epilepsy is a prevalent disease worldwide. Executive functions and social cognition are essential in daily living functioning, academic performance, and social adjustment. This study attempts to investigate the executive functions and ability to abstract social concepts in adolescents who have idiopathic generalized epilepsy and assess if the deterioration in executive functions can predict deterioration in the ability to abstract social concepts. Sixty adolescents with idiopathic generalized epilepsy aged between 12 and 19 collected from the neurology outpatient clinic at Sohag University Hospital in Upper Egypt were compared with 60 age- and sex-matched healthy adolescents regarding performance on executive function tests and ability to abstract social concepts tests. We used the Tower test to assess planning, the design fluency test to assess cognitive flexibility, the verbal fluency test to assess verbal fluency, and the Stroop test (overlapping between colour and word test) to assess inhibition and ability to abstract the social concepts test, which is composed of verbal part and performance part. Results Adolescents who have idiopathic generalized epilepsy have worse executive function impairment in all executive functions than control adolescents. Adolescents with idiopathic epilepsy have significantly more impairment in the ability to abstract social concepts (verbal and performance) compared to control adolescents. There is a significant correlation between executive functions and the ability to abstract social concepts (verbal and performance) in epileptic and control adolescents. Impairment in some executive functions can predict impairment in the ability to abstract social concepts (verbal and performance) in epileptic and control adolescents. Executive function impairment is correlated with the duration of illness, frequency of seizures per year, time since last epileptic fit, and presence of interictal epileptic discharge in EEG in the patient group. Conclusions Executive functions and the ability to abstract social concepts are significantly impaired in adolescents who have idiopathic generalized epilepsy. Impairment in executive functions can predict impairment in the ability to abstract social concepts. There is a need to screen executive functions and social abilities of adolescents with epilepsy and programmes to enhance these abilities.

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Section: Comparison To Previous Studiesmentioning

confidence: 99%

The ability of executive functions to predict deterioration in social abstraction in adolescents with idiopathic generalized epilepsy

Hadad

Ibrahim

Desoky

et al. 2022

Middle East Curr Psychiatry

View full text Add to dashboard Cite

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“…Research has shown a notable decrease in higher cognitive functions in patients with pediatric epilepsy compared to individuals without this condition. Deficiencies in various cognitive skills, particularly those involving executive functions, have been identified across multiple studies [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Enhancing Executive Functions in Pediatric Epilepsy: Feasibility and Efficacy of a Computerized Cognitive Training Program

Tapia,

Aras,

Duñabeitia

2024

Children

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Epilepsy, a prevalent neurological disorder characterized by recurrent seizures, significantly impacts individuals’ neurobiological, cognitive, and social lives. This report presents a feasibility study investigating the effects of a computerized cognitive training program on enhancing executive functions, particularly inhibitory control, in children and adolescents with epilepsy. Employing a pre-test–intervention–post-test design, the study involved 26 participants with diverse epileptic syndromes, focusing on those without severe intellectual disabilities. The intervention, based on the CogniFit Inc. platform, consisted of personalized tasks aiming to improve participants’ inhibitory skills over 16 weeks, with an average of 40 sessions completed per participant. Results indicated significant improvements in reaction times and error rates in an anti-saccade task, demonstrating enhanced inhibitory control and general performance post-intervention. These findings suggest that targeted cognitive training is a feasible approach to bolster executive functions in young individuals with epilepsy, potentially improving their academic performance, employability, and social interactions. The study underscores the importance of early cognitive interventions in epilepsy management, highlighting the potential for computerized programs to aid in mitigating cognitive deficits associated with the condition.

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Neurocognitive profile in patients with idiopathic generalized epilepsies: Differences between patients, their biological siblings, and healthy controls

Javůrková

Zivnustka

Brezinova

et al. 2023

Epilepsy & Behavior

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The Impact of Idiopathic Generalized Epilepsy on Executive Functions

Cited by 5 publications

References 11 publications

The ability of executive functions to predict deterioration in social abstraction in adolescents with idiopathic generalized epilepsy

The ability of executive functions to predict deterioration in social abstraction in adolescents with idiopathic generalized epilepsy

Enhancing Executive Functions in Pediatric Epilepsy: Feasibility and Efficacy of a Computerized Cognitive Training Program

Neurocognitive profile in patients with idiopathic generalized epilepsies: Differences between patients, their biological siblings, and healthy controls

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