2024
DOI: 10.2147/jir.s446199
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The Impact of Laparoscopic Appendectomy and Open Appendectomy on B7-H3-Mediated Intrinsic Immune Response in Children with Acute Suppurative Appendicitis

Chunsheng Duan,
Yuan Li,
Jiansu Ma
et al.

Abstract: Surgery impairs immune function and increases postoperative complications. B7H3, a co-stimulatory molecule, plays a crucial role in immune regulation. The present study examined the impact of B7H3 on the postoperative immune response in children with acute suppurative appendicitis (ASA) by comparing preoperative and postoperative B7H3 levels in laparoscopic surgery (LA) and open appendectomy (OA). Patients and Methods: 198 pediatric ASA patients were enrolled. The researcher group performed LA, while the contr… Show more

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