The Impact of Lifestyle Interventions in High-Risk Early Breast Cancer Patients: A Modeling Approach from a Single Institution Experience

Abstract

A healthy lifestyle plays a strategic role in the prevention of BC. The aim of our prospective study is to evaluate the effects of a lifestyle interventions program based on special exercise and nutrition education on weight, psycho-physical well-being, blood lipid and hormonal profile among BC patients who underwent primary surgery. From January 2014 to March 2017, a multidisciplinary group of oncologists, dieticians, physiatrists and an exercise specialist evaluated 98 adult BC female patients at baseline and at different time points. The patients had at least one of the following risk factors: BMI ≥ 25 kg/m2, high testosterone levels, high serum insulin levels or diagnosis of MS. Statistically significant differences are shown in terms of BMI variation with the lifestyle interventions program, as well as in waist circumference and blood glucose, insulin and testosterone levels. Moreover, a statistically significant difference was reported in variations of total Hospital Anxiety and Depression Scale (HADS) score, in the anxiety HADS score and improvement in joint pain. Our results suggested that promoting a healthy lifestyle in clinical practice reduces risk factors involved in BC recurrence and ensures psycho-physical well-being.

Physical Activity, Insulin Resistance and Cancer: A Systematic Review

“…Subsequently, a total of 19 studies met these criteria, leading to a comprehensive full-text evaluation. Ultimately, after the full-text assessment, 12 studies [23][24][25][26][27][28][29][30][31][32][33][34], aligning with the inclusion criteria, were incorporated into this systematic review. The study selection process is visually represented in the flow diagram provided (Figure 1).…”

The Effectiveness of Wearable Devices in Non-Communicable Diseases to Manage Physical Activity and Nutrition: Where We Are?

“…The emerging literature contains many examples of interventions, in which physical activity and nutrition are part of the same model, some of which are applied to populations living with NCDs, and the results demonstrate that this can be a model to scale up [ 97 , 98 , 99 ]. The success and feasibility of introducing this new model of care, which complements standard care, requires the implementation of specific action plans that may differ from country to country.…”

Home-based lifestyle intervention for breast cancer survivors: A surprising improvement in the quality of life during the first year of COVID-19 pandemic

“…In the Italian context, the growing literature on the population with BC suggests the effectiveness of a multidisciplinary approach to achieve and maintain HRQoL in the long term. This represents, today, a real challenge in the daily clinical practice because dealing with oncological disease requires an integration between scientific and clinical fields to decline the work in an “active” way by intervening on reality in a concrete and translational manner [ 24 , 28 – 30 ].…”