Article Highlights• Magno-modified Fenton process is used for remediating 2-methylpropane-2-thiol polluted soil • H 2 O 2 , NaOH, Fe 3 O 4 and ethanol concentrations in the magnetic field are the influencing factor • The batch reactor exposed to the magnetic field is a good way of separating Fe 3 O 4 • H 2 O 2 /nanoFe 3 O 4 and NaOH/nanoFe 3 O 4 are the influencing interaction with a positive role • NanoFe 3 O 4 /ethanol, H 2 O 2 /NaOH and magnetic field/nanoFe 3 O 4 have a negative role in the remediation yield AbstractIn this work, the nano-magno-modified Fenton process for remediation of soil polluted with 2-methylpropane-2-thiol is investigated. In this two-step oxidation process, a nanocatalyst system is used, including Fe 2+ /Fe 3+ coupled with ethanol solvent exposed to the magnetic field. The data analysis resulting from analysis of variance shows that H 2 O 2 , NaOH, Fe 3 O 4 nanoparticle and ethanol concentration with magnetic field intensity are effective on 2-methylpropane-2--thiol removal efficiency (26.99, 4.36, 3.42, 17.63 and 8.66%, respectively). Moreover, H 2 O 2 /nanoFe 3 O 4 and NaOH/nanoFe 3 O 4 were the influencing interaction with a positive role and nanoFe 3 O 4 /ethanol, H 2 O 2 /NaOH and magnetic field/nanoFe 3 O 4 with a negative role.The maximum level of initial H 2 O 2 concentration, a minimum level of ethanol and certain levels of NaOH initial concentration (8.64 mass%), Fe 3 O 4 nanoparticles to soil ratio and magnetic field intensity (0.11 mass% w/w and 3585 Oe, respectively) were suggested for the maximum contaminant remediation efficiency in the studied interval (%R = = 92.02). The magno-modified Fenton process could be used for both, increasing the removal efficiency and minimizing the vaporization of similar organosulfur compounds. Experimental results show that the solvent addition for diluting thiol contaminant could reduce the removal efficiency while the coupling of Fe 3 O 4 and magnetic field is a good way of separation and reuse to solve the recovery problem of the nanoparticles.