Additive manufacturing (AM), also known as 3D printing, has become an important manufacturing method, especially in the medical field. AM enables patient-specific instruments, prosthetics, prototypes, pre-operative models, implants, surgical cutting and drill guides, and even organ replacements, which are costlier if manufactured in other ways. [1][2][3][4][5] Nevertheless, this technology still must overcome some limitations to ensure safe and reproducible performance, for invasive medical applications. In particular, for long-term applications such as permanent implants, the material, and the printed part have to fulfill strict requirements in terms of biocompatibility and mechanical performance. [6] Additively manufactured specimens most likely show anisotropic and weaker mechanical properties compared to specimens produced via injection molding or subtractive manufacturing, mainly due to the lower inter-and intra-layer bonding as well as the presence of numerous weld lines. This is specifically true for parts manufactured by material extrusion (MEX) additive manufacturing methods. [7][8][9] However, several investigations on setting different parameters in MEX and their influence on the mechanical properties of printed specimens have already been performed with the aim of maximizing the mechanical performance of MEX parts. [7,[10][11][12][13][14][15] On the contrary, not much work has yet been done with the novel AM technology known as the ARBURG plastic freeforming (APF), [11][12][13]16] and the effects of