“…8,9,15 Moreover, previous studies included a few number of patients, focused in specific heart failure phenotypes (Heart failure with reduced ejection fraction) and did not address psycho-social limitations in a comprehensive manner. 7,[12][13][14] Given the limitations above mentioned, our study was designed to identify the clinical and, particularly, the psycho-social factors independently associated with selfcare in a broad-spectrum cohort of real-world patients with chronic HF. Importantly, we evaluated the influence of heart failure-related clinical and psycho-social factors on self-care (globally and each of the 3 domains) to ascertain their relative contribution that may help to guide interventions in the future aimed to improve self-care behaviours.…”