“…Multiple long term conditions are associated with a wide range of adverse outcomes for individuals and the health system. These included: increased health service use (14,56,79,(89)(90)(91)(92), polypharmacy (56,90,(93)(94)(95)(96), hospital admissions (14,79,89,90,97,98), out-of-pocket expenses (99-103), and psychological distress (79,93,(104)(105)(106), along with reductions in physical functioning (79,(107)(108)(109)(110)(111)(112), quality-of-life (14,79,(113)(114)(115)(116)(117), employability (118)(119)(120),and continuity of care (56,93,121,122).…”