The impact of nutritional status, physical function, comorbidity and early versus late start in dialysis on quality of life in older dialysis patients

Abstract

Our results indicate that physical function is important to all QoL aspects. Increased focus on physical rehabilitation seems pertinent. Early start of dialysis treatment was not associated with better long term QoL scores.

Predictors of quality of life in patients with end-stage renal disease on hemodialysis

“…3,4 Nutritional deficits and diet restrictions are frequent problems that imply negative health outcomes with high mortality risk and QOL deterioration. 7 Poor physical health and mental health are highly reported in this population and the latter is an independent risk factor for mortality in patients on dialysis. 1,4 Physical function decline is a prevalent feature in HD population and seems to affect negatively QOL even for younger HD patients.…”

“…3,4 The assessment of QOL of ESRD patients (physical, mental, and social well-being) has become an essential tool to develop better plans of care (preventive and treatment strategies) and a recommended routine clinical practice. 1,6 Comorbid disorders are prevalent in chronic kidney disease patients, such as depression (30% of ESRD patients), sexual dysfunction (nearly half of ESRD), and problems with sleep (up to 40%-80%), ranging from insomnia, sleep apnea to restless leg syndrome, and are associated with mortality as well as QOL, 7 all of which contribute to worse QOL. Nutritional status is an important determinant.…”

“…Preserving residual kidney function, but not early dialysis treatment as found in the IDEAL (initiating dialysis early and late) study, have also been associated with better scores. 7 Other factors are HD duration, age, and ethnicity. 3 Most of these associations are reported based on observational studies, and HRQOL domains lack randomized control trials describing the potential causality, effect, or interventions in those areas.…”

Health-related Quality of Life Among Patients With Chronic Kidney Disease of Unknown Etiology (CKDu) of an Agricultural Community in Kebithigollawa, Sri Lanka  

“…Nevertheless in the systematic review done by Spiegel and colleagues, they concluded that nutritional biomarkers including creatinine and albumin had a strong correlation with the physical domains of the HRQOL in ESRD patients [38]. Therefore, it is essential to maintain the nutritional parameters and physical performance emphasizing on physical rehabilitation for an overall wellbeing of patients [39].…”

Avaliação da qualidade de vida em pacientes em hemodiálise e sua relação com índice de massa corporal e creatinina sérica

“…Enquanto, no domínio lista de sintomas e o escore total do KDQOL-SF, aqueles com IMC<25kg/m², tiveram melhores resultados. Quando comparado com outros estudos (KALANTAR-ZADEH et al, 2001;LAEGREID et al, 2014;RAMOS et al, 2015), o presente teve melhor escore no componente mental. Com relação aos sintomas da doença renal, deve-se ressaltar o aumento das dores musculares, cãibras, falta de ar e fraqueza relatados durante o preenchimento do questionário, que são sintomas esperados em maior ou menor intensidade na clínica do paciente.…”