The Impact of Obesity on Surgical Complications and Disease Recurrence in Endometrial Cancer: A Retrospective Study of 267 Patients

Gaballa, Khaled; Abdelkhalek, Mohamed; Refky, Basel; Gadelhak, Basma; Aboelnaga, Engy M.; El-Beshbishi, Wafaa

doi:10.21608/resoncol.2020.23506.1089

Cited by 1 publication

(3 citation statements)

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“…However, obesity did not significantly impact the surgical procedures in the three groups of this study. Similar to our results, Gabala et al 10 reported that obesity did not affect the surgical techniques in endometrial cancer. In a study by Erkanli et al, 15 they investigated the effect of BMI on clinical and pathologic features and surgical morbidity in 42 patients with endometrial cancer.…”

Section: Discussionsupporting

confidence: 93%

“…Similar to previous studies, we detected that postoperative complication rates did not differ significantly between the obese and non-obese patient groups. 10 11 15 16 On the contrary, Bouwman et al 17 reported that elevated BMI was associated with an increased risk of postoperative surgical complications in morbidly obese patients who underwent laparotomy. Patients' characteristics may explain these different results, and they also depend on surgeons' experience and type of equipment.…”

Section: Discussionmentioning

confidence: 99%

“…Many studies have established that obese patients are at a higher risk of perioperative and postoperative complications, such as longer hospital stay and increased morbidity, even when minimally invasive surgeries or laparotomy are performed. 9 10 11 Obesity is defined by the World Health Organization (WHO) by using the body mass index (BMI) cutoff point of > 30 kg/m 2 , which is calculated as weight in kg divided by height in meters squared. Body mass index has significant public health importance because it correlates well with morbidity and/or mortality and endometrial cancer risk.…”

Section: Introductionmentioning

confidence: 99%

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Association of Obesity and Surgery Outcomes in Patients with Endometrial Cancer: A Single-Center Analysis

Dogan

2022

Rev Bras Ginecol Obstet

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Objective Although obesity can result in high morbidity and mortality in surgical outcomes because of multiple comorbidities, determinants of outcome in obese patients who underwent endometrial cancer surgery remain unclear. The aim of this study is to assess the relationship between body mass index (BMI) and surgical outcomes in obese patients with endometrial cancer. Methods An institutional retrospective review of the demographic details, clinical characteristics, and follow-up data of 142 patients with endometrial cancer who underwent surgery during a 72-month period was performed. The patients were divided into three groups based on their BMI; patients with BMI < 25 were identified as normal weight, patients with BMI between 25 and 30 were accepted as overweight, and those with BMI ≥ 30 kg/m2 were identified as obese. The groups' demographic and clinical variables were compared. Results Of the 142 patients, 42 were in the normal weight group, 55 in the overweight group, and 45 in the obese group. Age, surgical procedures, blood loss, preoperative health status, and metastatic lymph nodes did not show a significant difference between groups. However, surgery time and total lymph nodes were higher in the obese group. (p = 0.02, p = 0.00, and p = 0.00, respectively). Common complications were anemia, fever, intestinal injury, deep vein thrombosis, fascial dehiscence and urinary infection. There was no significant difference according to the complications. Conclusion Our results indicated that higher BMI was significantly associated with a longer duration of endometrial cancer surgery. Minimally invasive surgeries and conventional laparotomy could be performed safely in obese patients.

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Section: Discussionsupporting

confidence: 93%