The present work was carried out at a private Farm in Sammenoud area, Gharbieh Governorate during the two successive seasons of 2011-2012 and 2012-2013. The present study aimed to investigate the effect of bio fertilizers (VAM fungi and phosphorine) and foliar spray of plant extracts (garlic and aloe) on some vegetative growth (plant height, fresh and dry weight) essential oil percentage and chemical constituents of sage (Salvia officinalis L.) plant under different water stress conditions (plants irrigated every 15, 30 and 45 days). The results showed that irrigation of plants every 15 and 30 days were effective in increasing the productivity of vegetative growth, essential oil percentage and uptake of N,P and K % in sage. Spraying plants with garlic extract was more effective than aloe extract at in improving the productivity of vegetative growth, essential oil percentage and uptake of N, P and K content. Plants treated with VAM fungi were effective in increasing the productivity of vegetative growth, essential oil percentage and uptake of N, P and K %.