The Impact of Ozone Therapy on Antioxidant Status and Quality of Life in Palliative Care - Exploratory Study

Abstract

There is a constant concern about finding new or alternative therapeutical approaches for symptom control and quality of life that are essential in palliative care. Ozone therapy has been studied for over a century, since the development of the first medical ozone-generator able to ensure a correct titration of the ozone-oxygen mixture. When used in precise therapeutic doses O3 prove many consistent and safe therapeutic benefits, with minimal and preventable side actions. Our prospective exploratory study aimed to analyze the effects of ozone therapy administration on palliative care patients, by dynamically monitoring the antioxidant status (superoxide-dismutase and glutathione-peroxidase serum levels), pain perception, and quality of life. The results confirm ozone therapy as a promising alternative adjuvant therapy for increasing the quality of life in palliative care services.

The Role of Medical Ozone in Improving Antioxidant Status in Multiple Drug-Resistant Tuberculosis Patients: A Quasi-experimental Study

“…The present study demonstrates the role of ozone therapy in improving the antioxidant activity in immunecompromised conditions such as tuberculosis. The results are identical to the previous in vitro and vivo stud- ies conducted which demonstrated a reduction in oxidative stress and enhanced antioxidant defense mechanisms post ozone interventions (14)(15)(16)(17)(18). Furthermore, ozone is reckoned as a strong anti-microbial agent that can destroy the cellular cavities as well as reduce the reproductive capacity of the microbial cells (16,23).…”

“…Furthermore, ozone is reckoned as a strong anti-microbial agent that can destroy the cellular cavities as well as reduce the reproductive capacity of the microbial cells (16,23). Ozone improves the cellular redox balance and increases the oxygen uptake by the cells (13,14). This action supplements the innate immunity of the body (24).…”

“…Ozone, a molecule discovered in the mid-19th century, has shown to optimize anti-oxidant systems and metabolic functions of the body. The antioxidant property of ozone is attributed to its strong oxidizing property (13,14). Thus it can restore the cellular redox balance which is impaired in infectious diseases like TB (14,15).…”

“…The antioxidant property of ozone is attributed to its strong oxidizing property (13,14). Thus it can restore the cellular redox balance which is impaired in infectious diseases like TB (14,15). In 1991 Priimak et al demonstrated that a mixture of ozone and oxygen can reduce the reproductive capacity of Mycobacterium tuberculosis which is suggestive that the use of ozone and oxygen mix can be promising intervention in the management of TB (16).…”