The impact of passive hyperthermia on human attention networks: An fMRI study

Li, Kai; Sun, Gang; Li, Bo; Jiang, Qingjun; Yang, Xiao; Li, Min; Li, Li; Qian, Shaowen; Zhao, Lun; Zhou, Zhenyu; Deneen, Karen M. von; Liu, Yijun

doi:10.1016/j.bbr.2013.01.013

Cited by 72 publications

(89 citation statements)

References 78 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…First, the new ANT scores may eliminate impacts from inter-network interactions more successfully than the old ANT scores; second, the new method is demonstrated to be more reliable than the old method; third, the new method allows us to directly estimate the inter-network influences. Considering the widely usage of the ANT in studying genetic and neural mechanisms of attention networks [2], [55] and in investigating the abnormal attention networks in various diseases [19], [21]–[23], [30], [53], more pure and reliable markers are of vital importance for better estimating attention networks.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A New Method for Computing Attention Network Scores and Relationships between Attention Networks

et al. 2014

View full text Add to dashboard Cite

The attention network test (ANT) is a reliable tool to detect the efficiency of alerting, orienting, and executive control networks. However, studies using the ANT obtained inconsistent relationships between attention networks due to two reasons: on the one hand, the inter-network relationships of attention subsystems were far from clear; on the other hand, ANT scores in previous studies were disturbed by possible inter-network interactions. Here we proposed a new computing method by dissecting cue-target conditions to estimate ANT scores and relationships between attention networks as pure as possible. The method was tested in 36 participants. Comparing to the original method, the new method showed a larger alerting score and a smaller executive control score, and revealed interactions between alerting and executive control and between orienting and executive control. More interestingly, the new method revealed unidirectional influences from alerting to executive control and from executive control to orienting. These findings provided useful information for better understanding attention networks and their relationships in the ANT. Finally, the relationships of attention networks should be considered with more experimental paradigms and techniques.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Strong interactions between attention networks appeared in only half of these studies [9], [11], [24]–[28]. Some studies observed weak interactions [1], [29], but others failed to find any interactions [10], [13], [30], [31].…”

Section: Introductionmentioning

confidence: 95%

A New Method for Computing Attention Network Scores and Relationships between Attention Networks

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Interestingly, the deleterious effects of heat stress on prior assessments of cognitive function appear to be dictated by a similar mechanism, such that heat stress increases the neuronal demand of a cognitive task (39,55) and disrupts cerebral functional connectivity (18,25,38). Given that passive heat stress did not affect accuracy on any of the measured aspects of cognitive function in either group, but that agerelated differences persisted (Figs.…”

Section: Impact Of Agementioning

confidence: 99%

Cognitive and perceptual responses during passive heat stress in younger and older adults

Schlader

Gagnon

Adams

et al. 2015

American Journal of Physiology-Regulatory, Integrative and Comp

View full text Add to dashboard Cite

We tested the hypothesis that attention, memory, and executive function are impaired to a greater extent in passively heat-stressed older adults than in passively heatstressed younger adults. In a randomized, crossover design, 15 older (age: 69 Ϯ 5 yr) and 14 younger (age: 30 Ϯ 4 yr) healthy subjects underwent passive heat stress and time control trials. Cognitive tests (outcomes: accuracy and reaction time) from the CANTAB battery evaluated attention [rapid visual processing (RVP), choice reaction time (CRT)], memory [spatial span (SSP), pattern recognition memory (PRM)], and executive function [one touch stockings of Cambridge (OTS)]. Testing was undertaken on two occasions during each trial, at baseline and after internal temperature had increased by 1.0 Ϯ 0.2°C or after a time control period. For tests that measured attention, reaction time during RVP and CRT was slower (P Յ 0.01) in the older group. During heat stress, RVP reaction time improved (P Ͻ 0.01) in both groups. Heat stress had no effect (P Ն 0.09) on RVP or CRT accuracy in either group. For tests that measured memory, accuracy on SSP and PRM was lower (P Ͻ 0.01) in the older group, but there was no effect of heat stress (P Ն 0.14). For tests that measured executive function, overall, accuracy on OTS was lower, and reaction time was slower in the older group (P Յ 0.05). Reaction time generally improved during heat stress, but there was no effect of heat stress on accuracy in either group. These data indicate that moderate increases in body temperature during passive heat stress do not differentially compromise cognitive function in younger and older adults. cognitive function; aging; hyperthermia; thermal comfort ADULTS OVER THE AGE OF ϳ65 YR are at an increased risk of illness, injury, hospitalization, and death during heat waves (23, 29, 33-36, 63, 64). Age-related impairments in physiological responses to heat stress undoubtedly contribute to this increased risk (32). Heat-stressed older adults have attenuated increases in skin blood flow (30, 31) and sweating (26, 27), as well as impaired cardiovascular adjustments (42, 43). However, both physiological and psychological states influence health and safety (52, 53). Thus, a variety of factors may mediate the deleterious outcomes observed in the older population during heat waves.Healthy aging is associated with a general cognitive decline (49). Aspects of memory (4, 10, 12), attention (1, 12, 40), executive functioning (12,58,60), and processing speed (59) are typically [but not always (37, 48)] impaired with advancing age. This chronological cognitive decline may contribute to the risk of deleterious outcomes during heat waves in older adults by, for instance, leading to poor decision-making. Interestingly, perhaps because of the deleterious impact of heat stress on cerebral blood flow (46, 61) and/or disruptions in cerebral functional connectivity (66), many cognitive processes are impaired in heat-stressed younger adults [e.g., aspects of attention (19, 22, 65), memory (6, 19, 28, 41, 54), an...

show abstract

“…To truly understand the mechanics behind the observed effects, a richer assessment of the physiological impacts of heat on brain activity must be pursued to examine the specific relationships between brain activity and task performance under extreme heat conditions (Dalsgaard et al, 2003;Helton, 2010;Liu et al, 2013;Nielsen et al, 2001;Nielsen and Nybo, 2003;Paulus et al, 2009;Rasmussen et al, 2004). However, a significant challenge arises in the pursuit of this goal e the problem with performing neural assessments in extreme temperature environments.…”

Section: Discussionmentioning

confidence: 99%

“…However, a significant challenge arises in the pursuit of this goal e the problem with performing neural assessments in extreme temperature environments. For example, MRI equipment is almost exclusively located in temperaturecontrolled hospital environments, and this equipment is not designed to operate in extreme heat or cold (but see Jiang et al, 2013;Liu et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

Hot under the collar: The impact of heat on game play

et al. 2017

View full text Add to dashboard Cite

High temperatures have been documented to affect behavior in a variety of ways depending on the nature of the task. We extended this prior research by examining the effects of dynamically changing temperature on various aspects of performance in a video game task. In the span of approximately an hour, temperature was gradually increased, stayed constant for a period of time, and gradually decreased to baseline. The gaming task was a variation on one used to assess impulsivity in participants thus allowing the possibility of assessing the effects of temperature on impulsive choice. Rather than heat increasing impulsivity and thus decreasing wait times, participants showed increases in wait times as temperature increased which either suggests that participants were becoming more self-controlled under heat or that the documented negative impact of heat on motor functioning was dominating their performance. Importantly, the participant's sensitivity to the changing task requirements was not affected by changes in temperature.

show abstract

The impact of passive hyperthermia on human attention networks: An fMRI study

Cited by 72 publications

References 78 publications

A New Method for Computing Attention Network Scores and Relationships between Attention Networks

A New Method for Computing Attention Network Scores and Relationships between Attention Networks

Cognitive and perceptual responses during passive heat stress in younger and older adults

Hot under the collar: The impact of heat on game play

Contact Info

Product

Resources

About