The Impact of Peri-operative Enteral Immunonutrition on Post-operative Complications in Gastrointestinal Cancer Surgery: A Meta-Analysis

Khan, Ayman; Wong, Jean; Riedel, Bernhard; Laing, Erin; Beaumont, Anna; Kong, Jessica; Warrier, Satish; Heriot, Alexander G.

doi:10.1245/s10434-023-13265-1

Cited by 10 publications

(3 citation statements)

References 67 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The analysis of keywords and thematic clustering offers an intriguing insight into the current thematic areas of interest within the field. The identification of clusters related to pharmaconutrients, surgical approaches, inflammation, and specific cancer types reflects the multifaceted nature of immunonutrition and its impact on cancer 6 , 51 . These clusters highlight the need to explore the fundamentals of immunonutrition, the effects of specific nutrients on immune cell function, and their influence on tumor microenvironments 17 , 52 .…”

Section: Discussionmentioning

confidence: 99%

Mapping the landscape of immunonutrition and cancer research: A comprehensive bibliometric analysis on behalf of NutriOnc Research Group

De Felice,

Cattaneo,

Poto

et al. 2023

International Journal of Surgery

View full text Add to dashboard Cite

The ongoing global health challenge of cancer is driving the pursuit of innovative avenues for prevention, treatment, and enhanced outcomes. The convergence of nutrition and immune modulation, known as immunonutrition, is ready to act as a catalyst for transformative change in cancer research and therapy. Our study employs a bibliometric analysis to uncover the evolving trends within immunonutrition and cancer research across the past 25 years. Bibliometric data, including authors, journals, affiliations, and countries, were analyzed using the Bibliometrix R package. Clustering algorithms were applied to keywords to identify thematic areas and their evolution. A total of 489 documents were analyzed, showing an annual growth rate of 8.7%, with a collaboration index of 5.41, highlighting comprehensive multidisciplinary involvement within this landscape. Core authors demonstrated sustained productivity, while occasional authors indicated widespread interest. The Medical University of Warsaw led in institutional contributions. Country-wise, Italy, France, and the USA emerged as forerunners in fostering research productivity. Key journals like “Clinical Nutrition” served as beacons, emphasizing the multidimensional nature of this topic. The analysis highlighted growing research output and several collaborations, indicating the importance of immunoenriched nutrition in cancer treatment. The interplay of core authors and diversified engagement harmoniously accentuates the cross-disciplinary nature of this burgeoning field. International collaboration facilitated knowledge exchange. Prominent documents shaped the field, emphasizing the significance of nutritional interventions. Thematic clusters revealed varied focuses, including pharmaconutrients, surgical approaches, inflammation, and specific cancers. The expanding research output suggests further development, particularly in exploring immunoenriched nutrition’s impact on cancer types and patient populations. The multidisciplinary nature and international collaborations enhance the field’s progress. Gaps in research underscore the need for original studies and personalized approaches. This study guides future research, informing evidence-based nutritional interventions and advancing cancer care practices.

show abstract

Section: Discussionmentioning

confidence: 99%

Mapping the landscape of immunonutrition and cancer research: A comprehensive bibliometric analysis on behalf of NutriOnc Research Group

De Felice,

Cattaneo,

Poto

et al. 2023

International Journal of Surgery

View full text Add to dashboard Cite

show abstract

“…120,126 RNA nucleotides have been shown a potential to modulate immune function and enhance intestinal healing and recovery from ischemia/reperfusion injury. 127 In consequence, it is not surprising that enteral immunonutrition formulas enriched with these nutrients might exhibit a potential for modulating the inflammatory response and improving clinical outcomes (ie, reduction in acquired infections). 120 A summary of practical recommendations for MNT in these patients is provided in Table 2.…”

Section: Nutrition In Clinical Practicementioning

confidence: 99%

“…Arginine enhances immune response (ie, natural killer cytotoxicity and T‐cell proliferation) and wound healing, which may be of importance against infections and after surgical procedures (eg, biopsy) 120,126 . RNA nucleotides have been shown a potential to modulate immune function and enhance intestinal healing and recovery from ischemia/reperfusion injury 127 . In consequence, it is not surprising that enteral immunonutrition formulas enriched with these nutrients might exhibit a potential for modulating the inflammatory response and improving clinical outcomes (ie, reduction in acquired infections) 120 …”

Section: Considerations In Guiding Mntmentioning

confidence: 99%

Considerations for medical nutrition therapy management of the critically ill patient with hematological malignancies: A narrative review

Lopez‐Delgado,

Patel,

Stoppe

et al. 2024

Nut in Clin Prac

View full text Add to dashboard Cite

Patients with hematological malignancies (HMs) are more frequently admitted now than in the past to the intensive care unit (ICU) due to more aggressive approaches in primary therapy of HMs and the need for critical care support. Pathophysiological alterations derived from HMs and the different hematological therapies, such as chemotherapy, negatively affect gastrointestinal (GI) function, metabolism, and nutrition status. Further, malnutrition strongly influences outcomes and tolerance of the different hematological therapies. In consequence, these critically ill patients frequently present with malnutrition and pathophysiological alterations that create challenges for the delivery of medical nutrition therapy (MNT) in the ICU. Frequent screening, gauging tolerance, and monitoring nutrition status are mandatory to provide individualized MNT and achieve nutrition objectives. The present review discusses how HM impact GI function and nutrition status, the importance of MNT in patients with HM, and specific considerations for guidance in providing adequate MNT to these patients when admitted to the ICU.

show abstract

Efficacy of Prehabilitation in Abdominal Cancer Surgery

Edbrooke,

Abo,

Denehy

2024

Recent Strategies in High Risk Surgery

View full text Add to dashboard Cite

The Impact of Peri-operative Enteral Immunonutrition on Post-operative Complications in Gastrointestinal Cancer Surgery: A Meta-Analysis

Cited by 10 publications

References 67 publications

Mapping the landscape of immunonutrition and cancer research: A comprehensive bibliometric analysis on behalf of NutriOnc Research Group

Mapping the landscape of immunonutrition and cancer research: A comprehensive bibliometric analysis on behalf of NutriOnc Research Group

Considerations for medical nutrition therapy management of the critically ill patient with hematological malignancies: A narrative review

Efficacy of Prehabilitation in Abdominal Cancer Surgery

Contact Info

Product

Resources

About