“…18,21 Mean duration of diabetes was 9.4 years (SDϭ7.9) (20 studies). Nineteen studies provided information regarding diabetes treatment, [17][18][19]21,28,29,31,38,39,41,43,44,48,49,54,59,60,63,64 and insulin was the treatment most often used. 18,19,21,28,29,31,38,41,43,44,48,49,54,60,63,64 The quality of the studies varied; in particular, randomization procedure and allocation concealment among RCTs were rarely reported, and a funnel plot suggested the possibility of publication bias.…”