The Impact of Postmastectomy Radiation Scar Boost on Local Recurrence Free Survival in High Risk Patients

Albert, Ashley; Mangana, S.H.; Weatherall, Lacey; Vijayakumar, S.

doi:10.1016/j.ijrobp.2018.07.1571

Cited by 1 publication

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“…A study of 339 patients by Shah et al, 18 including those with stage IV disease, found no significant difference in cumulative incidence of local recurrence between the group who received CWB and those who did not. In a more recent detailed report, Albert et al 27 analyzed 140 patientsd46 patients (33%) of whom did not receive CWB. There was no significant difference in local control between the 2 groups.…”

Section: Discussionmentioning

confidence: 99%

The Impact of Chest Wall Boost on Reconstruction Complications and Local Control in Patients Treated for Breast Cancer

Naoum

Salama

et al. 2019

International Journal of Radiation Oncology*Biology*Physics

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Chest wall boost (CWB) is a common practice in postmastectomy radiation therapy (PMRT) in the United States, where more than 65% of women receiving PMRT receive CWB. We studied 746 patients who received PMRT and reconstruction; 379 (51%) of them received Purpose: Giving an additional radiation dose to the incision or chest wall has been a practice, but it has never been studied in a randomized setting, and it might lead to inferior cosmetic outcomes. This study aims to evaluate whether delivery of a chest wall boost (CWB) to the mastectomy scar or chest wall is independently associated with reconstruction complications and to assess its disease control efficacy in the setting of breast reconstruction. Methods and Materials: We conducted a retrospective chart review of 746 patients with breast cancer who underwent mastectomy, breast reconstruction, and PMRT; all underwent treatment at our institution during 1997 to 2016. Various reconstruction techniques were used among this cohort including autologous reconstruction, singlestage direct-to-implant reconstruction, and 2-stage tissue expander implant. Cohorts were divided by administration of CWB. The primary objective was comparing the

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Section: Discussionmentioning

confidence: 99%