The impact of psychiatric comorbidities on the length of hospital stay in patients with heart failure

Carter, Paul; Reynolds, James M.; Carter, Andrew; Potluri, Siri; Uppal, Hardeep; Chandran, Suresh; Potluri, Rahul

doi:10.1016/j.ijcard.2016.01.132

Cited by 32 publications

(16 citation statements)

References 44 publications

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“…Nine studies compared the LOS of PWD and PwoD with regard to infectious, cardiovascular, or cerebrovascular diseases (Table and Appendix, Figure ) . Across different infectious diseases, PWD had a longer hospitalization ranging from 3 days in AIDS patients to 21.8 days in patients with urinary tract infection as compared to PwoD .…”

Section: Resultsmentioning

confidence: 99%

“…The 2 studies from Israel and the United States showed an on average 11.2 days (95% CI: 6.6‐15.7) and 0.9 days (95% CI: 0.9‐1.0) shorter LOS for PWD compared to PwoD, respectively. Hospitalizations due to cardiovascular diseases, including heart failure, acute coronary syndrome, and syncope/collapse, were assessed by 3 studies, all of which reported a longer LOS for PWD compared to PwoD. The difference ranged from 4.2 days in heart failure patients to 19.1 days in patients with syncope/collapse …”

Section: Resultsmentioning

confidence: 99%

“…Hospitalizations due to cardiovascular diseases, including heart failure, acute coronary syndrome, and syncope/collapse, were assessed by 3 studies, all of which reported a longer LOS for PWD compared to PwoD. The difference ranged from 4.2 days in heart failure patients to 19.1 days in patients with syncope/collapse …”

Section: Resultsmentioning

confidence: 99%

“…Nine studies compared the LOS of PWD and PwoD with regard to infectious, cardiovascular, or cerebrovascular diseases (Table 3 and Appendix, Figure A1). 15,61,[63][64][65]67,68 Across different infectious diseases, PWD had a longer hospitalization ranging from 3 days in AIDS 61 patients to 21.8 days in patients with urinary tract infection as compared to PwoD. 15 Four studies assessed the LOS in stroke patients, 2 of which reported a longer LOS for PWD from 6.5 to 12 days in Sweden 64 and Ireland.…”

Section: Los In Hospitalizations Due To Infectious Cardiovascularmentioning

confidence: 99%

“…, were assessed by 3 studies,15,67,68 all of which reported a longer LOS for PWD compared to PwoD. The difference ranged from 4.2 days in heart failure patients 67 to 19.1 days in patients with syncope/ collapse 15.…”

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confidence: 99%

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Length of hospital stay and dementia: A systematic review of observational studies

Möllers

Stocker

Wei

et al. 2018

Int J Geriat Psychiatry

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Objective Hospitalizations of people with dementia (PWD) are often accompanied by complications or functional loss and can lead to adverse outcomes. Unsystematic findings suggest an influence of comorbidities on the extent of differences in the length of hospital stay (LOS). This systematic review aimed to identify and evaluate all studies reporting LOS in PWD as compared to PwoD in general hospitals. Methods A systematic review of observational studies using PubMed and ISI Web of Knowledge. Inclusion criteria comprised original studies written in English or German, assessment of diagnosis of dementia, measurement of LOS, and comparison of people with and without dementia. Results Fifty‐two of 60 studies reported a longer hospitalization time for PWD compared to PwoD. The extent of the difference in LOS varied between and within countries as well as by type of primary morbidity (eg, injuries, cardiovascular diseases). The range of the LOS difference for studies without restriction to a primary morbidity was −2 to +22 days after matching or adjustment for a variable number and selection of potentially relevant covariates. For studies with injuries/fractures/medical procedures and infectious/vascular disease as the primary morbidity, the range was −2.9 to +12.4 and −11.2 to +21.8 days, respectively. Conclusions The majority of studies reported a longer hospitalization of PWD compared to PwoD. Length of hospital stay seems to be influenced by a variety of medical, social, organizational factors, including reasons for hospital admission, whose role should be explored in detail in further research.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Los In Hospitalizations Due To Infectious Cardiovascularmentioning

confidence: 99%

mentioning

confidence: 99%

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Length of hospital stay and dementia: A systematic review of observational studies

Möllers

Stocker

Wei

et al. 2018

Int J Geriat Psychiatry

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Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

Massussi,

Bellicini,

Adamo

et al. 2024

ESC Heart Failure

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Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease. Despite these insights, cognitive outcomes remain largely overlooked in heart failure management. This narrative review outlines the prevalence and risk of cognitive impairment in heart failure patients, exploring potential shared pathophysiological mechanisms and examining the impact of heart failure therapy on cognitive deficits. Additionally, it discusses clinical implications and suggests future treatment approaches targeting therapeutic outcomes. Cognitive impairment is prevalent among individuals with heart failure, with reported rates varying widely depending on assessment methods. Shared pathological pathways and risk factors, including atrial fibrillation (AF), hypertension, obesity and type 2 diabetes mellitus, suggest a causal link. Mechanisms such as poor perfusion, microembolic events, ischaemic syndromes and cerebral inflammation contribute to this relationship. Moreover, heart failure itself may exacerbate cognitive dysfunction. This emerging understanding posits that vascular dementia and Alzheimer's disease may represent a pathophysiological continuum, driven by both the accumulation of misfolded proteins and cerebrovascular pathology due to cardiovascular dysfunction. Understanding these links is crucial for developing effective treatment strategies. The complex interplay between heart failure and cognitive impairment underscores the necessity for a holistic patient care approach. Both conditions share analogous disease processes, influencing self‐management and independence in patients. Prioritizing brain health in heart failure management is essential to enhance patient prognosis and general well‐being.

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The burden of psychiatric illnesses in adult patients with beta-thalassemia: a 5-year nationwide inpatient evaluation in the United States

et al. 2018

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The impact of psychiatric comorbidities on the length of hospital stay in patients with heart failure

Cited by 32 publications

References 44 publications

Length of hospital stay and dementia: A systematic review of observational studies

Length of hospital stay and dementia: A systematic review of observational studies

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

The burden of psychiatric illnesses in adult patients with beta-thalassemia: a 5-year nationwide inpatient evaluation in the United States

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