The Impact of Psychological Functioning upon Systemic Sclerosis Patients’ Quality of Life

Hyphantis, Thomas; Tsifetaki, Niki; Siafaka, Vassiliki; Voulgari, Paraskevi V.; Pappa, Christina; Bai, Maria; Palieraki, K; Venetsanopoulou, Aliki; Mavreas, Venetsanos; Drosos, Alexandros A.

doi:10.1016/j.semarthrit.2007.03.008

Cited by 56 publications

(47 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Similar to the original version (6), the Greek version of the PHQ-9 was found to be unidimensional, with acceptable internal consistency. The study of the scale's convergent validity revealed that the PHQ-9 was most closely correlated with SCL-90-R depression and WHOQOL-BREF mental HRQOL, as expected, and its high positive correlation with functional disability, as well as its significant negative association with all aspects of HRQOL, being consistent with the results of previous studies (31)(32)(33), are further construct validity indicators.…”

Section: Discussionsupporting

confidence: 88%

Diagnostic accuracy, internal consistency, and convergent validity of the Greek version of the patient health questionnaire 9 in diagnosing depression in rheumatologic disorders

Hyphantis¹,

Kotsis²,

Voulgari³

et al. 2011

Arthritis Care & Research

Self Cite

View full text Add to dashboard Cite

Objective. The Patient Health Questionnaire 9 (PHQ-9) was developed to screen for depressive disorders in community, primary care, and medical settings. We aimed to estimate its diagnostic accuracy, internal consistency, reliability, and convergent validity in diagnosing major depressive disorder (MDD) in Greek patients with rheumatologic disorders. Methods. In a 2-phase sampling design study, we recruited 475 patients with established rheumatologic disorders. One of 2 of the high scorers (PHQ-9 score >9, n ‫؍‬ 85) and 1 of 3 of the low scorers (PHQ-9 score 0 -8, n ‫؍‬ 128) were interviewed using the Mini International Neuropsychiatric Interview to confirm MDD. A receiver operator characteristic curve analysis was performed to confirm the optimum threshold value. The scale's dimensional structure was tested with factor analysis, and internal consistency reliability was assessed with Cronbach's alpha. Psychological distress (Symptom Check List-90-Revised [SCL-90-R]), disability (Health Assessment Questionnaire disability index), and health-related quality of life (HRQOL; World Health Organization Quality of Life Instrument [WHOQOL-BREF]) were also assessed to test convergent validity with bivariate correlations.Results. At an optimum threshold of 10, the PHQ-9 showed a sensitivity of 81.2% and a specificity of 86.8%. The area under the curve was 0.91. The PHQ-9 presented unidimensional structure with good scale reliability (␣ ‫؍‬ 0.82). The PHQ-9 score presented the greatest correlations with SCL-90-R depression (r ‫؍‬ 0.736) and WHOQOL-BREF mental HRQOL scales (r ‫؍‬ ؊0.571), and all other correlations with disability and HRQOL were in the expected direction. Conclusion. At a cutoff of 10, the PHQ-9 is an accurate, reliable, and valid measure for screening for MDD among Greek rheumatologic patients.

show abstract

Section: Discussionsupporting

confidence: 88%

Diagnostic accuracy, internal consistency, and convergent validity of the Greek version of the patient health questionnaire 9 in diagnosing depression in rheumatologic disorders

Hyphantis¹,

Kotsis²,

Voulgari³

et al. 2011

Arthritis Care & Research

Self Cite

View full text Add to dashboard Cite

show abstract

“…Each item is rated on a 5-point Likert scale and the scores are transformed on a scale from 0 -100, where higher scores indicate better HRQOL. The WHOQOL-BREF is a cross-culturally valid assessment of HRQOL (39) with adequate validity in rheumatic diseases (42), and we used the Greek version as an outcome measure of HRQOL in Greek patients with rheumatic disease (41,43).…”

Section: Significance and Innovationsmentioning

confidence: 99%

Anxiety and depressive symptoms and illness perceptions in psoriatic arthritis and associations with physical health‐related quality of life

Kotsis¹,

Voulgari²,

Tsifetaki³

et al. 2012

Arthritis Care & Research

Self Cite

114

View full text Add to dashboard Cite

Objective. Symptoms of psychological distress, including anxiety and depressive symptoms, and illness perceptions are important in determining outcome in patients with rheumatic disease. We aimed to compare psychological distress in psoriatic arthritis (PsA) and rheumatoid arthritis (RA) and to test whether the association between psychological variables and health-related quality of life (HRQOL) was similar in the 2 forms of arthritis. Methods. In 83 PsA patients and 199 RA patients, we used the Patient Health Questionnaire 9 (PHQ-9), the Symptom Checklist-90-Revised, and the Brief Illness Perception Questionnaire to assess psychological variables and the World Health Organization Quality of Life Instrument, Short Form to assess HRQOL. We used hierarchical regression analysis to determine the associations between psychological variables and HRQOL after adjusting for demographic variables and disease parameters. Results. The prevalence of moderate to severe levels of depressive symptoms (PHQ-9 score >10) was 21.7% in PsA patients, 25.1% in RA patients, and 36.7% in those PsA patients with polyarthritis. After adjustment for severity of disease and pain, anxiety (␤ ‫؍‬ ؊0.28) and concern about bodily symptoms attributed to the illness (␤ ‫؍‬ ؊0.33) were independent correlates of physical HRQOL in PsA. In RA, depressive symptoms (␤ ‫؍‬ ؊0.29) and concern about the consequences of the arthritis (␤ ‫؍‬ ؊0.27) were independent correlates of physical HRQOL. Conclusion. These findings suggest strongly that psychological factors are important correlates of HRQOL in PsA as well as in RA. Attention to patients' anxiety and their concern about numerous bodily symptoms attributed to the illness may enable rheumatologists to identify and manage treatable aspects of HRQOL in PsA.

show abstract

“…The WHOQOL-BREF has been found to have adequate testretest reliability, internal consistency and factor structure in people with rheumatoid arthritis [51], it has been widely used in cancer [52] and evidence suggest that it should be considered a valid outcome measure for interventions that aim to improve quality of life [51]. We have also used previously the Greek version of the WHOQOL-BREF [50,53] as an outcome measure of HRQOL in Greek rheumatologic patients [25]. The physical HRQOL component of the WHOQOL-BREF was used as our primary outcome variable.…”

Section: Outcome (Physical Hrqol)mentioning

confidence: 99%

“…Little attention, however, has been given to the role that anxiety, depression or somatization play in the HRQOL of glaucoma patients [18,20]. Finally, in patients with established rheumatologic diseases (e.g., rheumatoid arthritis, systemic sclerosis or systemic lupus erythematosus), depression and general psychologic distress are independent correlates of impaired HRQOL [21][22][23][24][25], but somatization has not been studied in this context, in contrast to fibromyalgia.…”

Section: Introductionmentioning

confidence: 99%

Somatization is associated with physical health-related quality of life independent of anxiety and depression in cancer, glaucoma and rheumatological disorders

et al. 2009

Self Cite

View full text Add to dashboard Cite

show abstract

The Impact of Psychological Functioning upon Systemic Sclerosis Patients’ Quality of Life

Cited by 56 publications

References 36 publications

Diagnostic accuracy, internal consistency, and convergent validity of the Greek version of the patient health questionnaire 9 in diagnosing depression in rheumatologic disorders

Diagnostic accuracy, internal consistency, and convergent validity of the Greek version of the patient health questionnaire 9 in diagnosing depression in rheumatologic disorders

Anxiety and depressive symptoms and illness perceptions in psoriatic arthritis and associations with physical health‐related quality of life

Somatization is associated with physical health-related quality of life independent of anxiety and depression in cancer, glaucoma and rheumatological disorders

Contact Info

Product

Resources

About