The
impact of microgel particles onto a wall represents an elementary
process that determines the one-stage production of a biopolymer layer
on a nanofiber scaffold in the framework of tissue bioengineering.
The formation of a microgel layer is experimentally examined on a
hydrophobic uniform surface and a nonwoven polymer membrane made of
vinylidene fluoride–tetrafluoroethylene copolymer. In-air microfluidics
methods, namely, an external vibration disturbance on the microflow
of a cross-linkable biopolymer, make it possible to form the microstructures
of “beads-on-thread” with a uniform distance between
microgel particles of identical size (340–480 μm, depending
on the sample). The successive particle–surface and particle–particle
collisions are explored to develop the concept of technology for depositing
microgel particles on surfaces for mobile one-stage production of
microgel layers with a thickness of one and two particles, respectively.
A physical model of successive particle–surface and particle–particle
interactions is proposed. Empirical expressions are derived for predicting
the diameters of maximum spreading (deformation) and the minimum heights
of microgel particles on smooth and nanofiber surfaces, as well as
in particle–particle collisions using a dimensionless criterion
of gelation degree. The effect of microgel viscosity and fluidity
on the maximum particle spreading during successive particle–surface
and particle–particle collisions is elucidated. The consistent
findings have made it possible to develop a predictive method for
determining the growth dynamics of microgel layer area with a thickness
of one or two particles on a nanofiber scaffold within a few seconds.
The specific behavior of a microgel with a given gelation degree is
simulated to produce a layer.