Two field experiments were conducted out at the experimental farm of Malawi Agricultural Research station, Minia Governorate, Egypt during two seasons of 2021 and 2022 to study the effect of salicylic acid, inoculation with Bradyrhizobium japonicum bacteria on yield and yield components of some soybean (Glycine max L. Merrill.) cultivars. The obtained results summarized as follows: Data results that salicylic acid sprayed at 50 ppm produced the highest values of yield components (plant height, branches number/plant, height of the first pod, number of fruitful / main stem, number of pods/plants, number of seeds/pod, seed index, seed yield/plant), yield characters (seed yield/fed., straw yield/fed, harvest index% and land use efficiency (LUE) and seed chemical content (seed oil percentage, oil yield/fed., seed crude protein percentage and protein yield/fed. in both seasons. The lowest values obtained by salicylic acid sprayed at 0 ppm concentration in both seasons. The highest values of the mentioned traits from bacterial inoculation in the two seasons. Soybean cultivar Giza111 gave the highest values of the studied characters, followed by Giza 22 cultivar in both seasons. The highest values of the characters under study obtained from Giza 111 cultivar with salicylic acid sprayed at 50 ppm under inoculation, while the lowest one obtained by Giza 21 cultivar with 0 ppm salicylic acid under inoculation treatment in both seasons.