The impact of take-home naloxone distribution and training on opiate overdose knowledge and response: An evaluation of the THN Project in Wales

Bennett, Trevor; Holloway, Katy

doi:10.3109/09687637.2012.658104

Cited by 61 publications

(65 citation statements)

References 8 publications

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“…14,16,18,19 Clients reported feeling empowered and were more confident in responding to overdose events, which has been reported in other studies. 10,16,[19][20][21][22][23] Although not measured quantitatively, participants perceived that providing naloxone did not increase drug use or risk-taking behaviour, as has been observed by others. 21,22 Symptoms of withdrawal or aggression after the administration of naloxone were uncommon, even though more than 40% of the clients received 2 or more ampoules of naloxone.…”

Section: Discussionmentioning

confidence: 93%

“…10,16,[19][20][21][22][23] Although not measured quantitatively, participants perceived that providing naloxone did not increase drug use or risk-taking behaviour, as has been observed by others. 21,22 Symptoms of withdrawal or aggression after the administration of naloxone were uncommon, even though more than 40% of the clients received 2 or more ampoules of naloxone. This helps to alleviate concerns that naloxone administration in community settings will trigger withdrawal and aggression.…”

Section: Discussionmentioning

confidence: 93%

See 1 more Smart Citation

A quantitative and qualitative evaluation of the British Columbia Take Home Naloxone program

Banjo¹,

Tzemis

Al-Qutub

et al. 2014

CMAJ Open

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Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 93%

A quantitative and qualitative evaluation of the British Columbia Take Home Naloxone program

Banjo¹,

Tzemis

Al-Qutub

et al. 2014

CMAJ Open

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“…In addition to how to recognize and manage an overdose and effectively administer naloxone, the education and training curricula delivered by these programs often cover established risk factors for overdose (Clark et al, 2014). Several studies have reported increases in knowledge of overdose risk factors among opioid-users following participation in community-based overdose prevention trainings (Bennett and Holloway, 2012; McGregor et al, 2001; Strang et al, 2008); however, no recent study has assessed whether having or engaging in established overdose risk factors translates to higher perceived overdose risk among opioid users (McGregor et al, 1998). …”

Section: Introductionmentioning

confidence: 99%

Correlates of overdose risk perception among illicit opioid users

Rowe

Santos

Behar

et al. 2016

Drug and Alcohol Dependence

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Background Opioid-related mortality continues to increase in the United States. The current study assesses demographic and behavioral predictors of perceived overdose risk among individuals who use opioids illicitly. By examining these correlates in the context of established overdose risk factors, we aim to assess whether characteristics and behaviors that have been associated with actual overdose risk translate to higher perception of risk. Methods We conducted a cross-sectional survey of 172 adult illicit opioid users in San Francisco, CA and used multivariable logistic regression to identify predictors of perception of high risk for opioid overdose. Results Age (aOR=0.96, 95%CI=0.93-1.00) and number of injection days per month (0.91, 0.86-0.97) were associated with a lower odds of perceived high overdose risk. There was no independent association between use of opioid analgesics, concurrent use of opioids and benzodiazepines or cocaine, or HIV status and overdose risk perception. Conclusions Opioid users who injected more frequently and those who were older were less likely to perceive themselves as being at risk of overdose, notwithstanding that those who inject more are at higher risk of overdose and those who are older are at higher risk overdose mortality. In addition, despite being established overdose risk factors, there was no relationship between use of opioid analgesics, concurrent use of opioids and cocaine or benzodiazepines, or self-reported HIV status and overdose risk perception. These findings highlight key populations of opioid users and established risk factors that may merit focused attention as part of education-based overdose prevention and opioid management strategies.

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“…6 Program evaluations suggest that community-based overdose education and naloxone distribution is an effective strategy to prevent overdose fatalities. [7][8][9][10][11][12] Community-based programs have traditionally served people who use heroin and nonmedical opioids, but a significant proportion of overdose deaths are related to opioids prescribed for pain. [13][14][15][16][17] In the Veteran's Administration and large managed care organizations, the overdose risk is particularly high in people prescribed more than 100 milligrams morphine equivalent daily doses.…”

Section: Introductionmentioning

confidence: 99%

Overdose Education and Naloxone for Patients Prescribed Opioids in Primary Care: A Qualitative Study of Primary Care Staff

et al. 2015

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BACKGROUND:The rate of fatal unintentional pharmaceutical opioid poisonings has increased substantially since the late 1990s. Naloxone is an effective opioid antidote that can be prescribed to patients for bystander use in the event of an overdose. Primary care clinics represent settings in which large populations of patients prescribed opioids could be reached for overdose education and naloxone prescription. OBJECTIVE: Our aim was to investigate the knowledge, attitudes and beliefs about overdose education and naloxone prescription among clinical staff in primary care. DESIGN: This was a qualitative study using focus groups to elucidate both clinic-level and provider-level barriers and facilitators. SETTING: Ten primary care internal medicine, family medicine and infectious disease/HIV practices in three large Colorado health systems. METHODS: A focus group guide was developed based on behavioral theory. Focus group transcripts were coded for manifest and latent meaning, and analyzed for themes using a recursive approach that included inductive and deductive analysis. RESULTS: Themes emerged in four content areas related to overdose education and naloxone prescription: knowledge, barriers, benefits and facilitators. Clinical staff (N= 56) demonstrated substantial knowledge gaps about naloxone and its use in outpatient settings. They expressed uncertainty about who to prescribe naloxone to, and identified a range of logistical barriers to its use in practice. Staff also described fears about offending patients and concerns about increased risk behaviors in patients prescribed naloxone. When considering naloxone, some providers reflected critically and with discomfort on their own opioid prescribing. These barriers were balanced by beliefs that prescribing naloxone could prevent death and result in safer opioid use behaviors. LIMITATIONS: Findings from these qualitative focus groups may not be generalizable to other settings. CONCLUSION: In addition to evidence gaps, logistical and attitudinal barriers will need to be addressed to enhance uptake of overdose education and naloxone prescription for patients prescribed opioids for pain.

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The impact of take-home naloxone distribution and training on opiate overdose knowledge and response: An evaluation of the THN Project in Wales

Cited by 61 publications

References 8 publications

A quantitative and qualitative evaluation of the British Columbia Take Home Naloxone program

A quantitative and qualitative evaluation of the British Columbia Take Home Naloxone program

Correlates of overdose risk perception among illicit opioid users

Overdose Education and Naloxone for Patients Prescribed Opioids in Primary Care: A Qualitative Study of Primary Care Staff

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