The impact of the clinical pharmacist-led interventions in China: A systematic review and Meta-Analysis

Qin, Si-bei; Zhang, Xinyi; Fu, Yu; Nie, Xiaoyan; Liu, Jian; Shi, Luwen; Chen, Yimin

doi:10.1007/s11096-020-00972-y

Cited by 18 publications

(16 citation statements)

References 18 publications

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“…20 A meta-analysis conducted by Qin et al showed that type of disease and type of pharmacist intervention impact the effectiveness of clinical pharmacist intervention. 21 Limitations of this study were the variety of clinical pharmacist's competency and the lack of study period.…”

Section: Discussionmentioning

confidence: 95%

Clinical Pharmacist’s Role in Optimizing Therapy through Drug-Related Problems Identification

Debora

Susanti²,

Suharjono

2021

Indones J Clin Pharm

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Clinical pharmacists play an important role in a clinical setting as part of a team. Drug-related problem (DRP) is the main part pharmacist should focus on to achieve the optimal therapy for patients. Therefore, this study aimed to investigate the role of clinical pharmacy in a private hospital of West Java, Indonesia, and describe the prevalence of DRPs and several factors associated with the risk of DRPs. The clinical pharmacist's monthly report was obtained from June to August 2020. Furthermore, problems, causes, and types of DRP were identified using PCNE Classification V9.1. Drug classes and other factors related to DRP were also investigated. This was a descriptive study with a retrospective approach to medical records, where 240 DRPs were identified in 157 patients. Approximately 4.45% experienced DRP, especially in ICU at 45.83% and Stroke Unit or SU-IC at 25.42%. The most common DRPs were incomplete drug treatment, drug interaction, and dose adjustment. Antimicrobial, cardiovascular agents, and PPI were the most commonly involved. In the linear regression analysis, length of stay and number of therapy significantly affect DRP. In this study, pharmacists intervented each DRP, with 57% accepted as fully and partially implemented by the physicians. A total of 22% of interventions ended with unknown status due to limited follow-up time. Meanwhile, reviews on medication by clinical pharmacists lead to improvement in drug treatment. The implementation of clinical pharmacy services shows many DRPs to be prevented and increases therapy optimization.

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Section: Discussionmentioning

confidence: 95%

Clinical Pharmacist’s Role in Optimizing Therapy through Drug-Related Problems Identification

Debora

Susanti²,

Suharjono

2021

Indones J Clin Pharm

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“…In China, pharmaceutical services developed rapidly recent years since the Chinese Ministry of Health firstly proposed to establish a clinical pharmacist system in hospitals in 2002 (11). A recent systematic review has shown that in China, the pharmacistled intervention could significantly reduce the length of hospitalization, readmission rate and mortality during hospital of patients (12). Due to the personal shortage in majority of hospitals, it is unrealistic to apply personalcentered pharmaceutical services to all patients (13).…”

Section: Role Of Clinical Pharmacistsmentioning

confidence: 99%

Pharmaceutical services based on therapeutic care pathway for kidney transplantation from donors of infants and young children: a single-center experience

Wen

Zhao

et al. 2022

Transl Pediatr

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Background: The pharmaceutical services based on therapeutic care pathway for kidney transplantation from infants and young children (age <3 years, weight <15 kg) to pediatric recipients can detect and resolve medication-related problems. In this paper, we report our experience on pharmaceutical services based on therapeutic care pathway to evaluate the therapeutic effects and assess the feasibility of perioperative treatment protocols. Methods:We performed a retrospective study of 12 recipients who received their graft from infants and young children, between September 2011 and December 2013 at our institution. As providers of pharmaceutical services, the clinical pharmacists collected and reviewed the clinical data from all patients, including the clinical characteristics, outcome indices, and follow-up dates. A three-step-protocol of pharmaceutical services including clinician's application, pharmacist consultation, and ongoing direct pharmaceutical care and follow-up was used through the entire length of patient's admission, hospitalization, and discharge. This protocol was developed and refined based on the guidelines for transplant perioperative treatment and experiences of the clinical pharmacists to standardize the workflow, and improve the medical treatment and quality of life of patients.Results: There was no acute rejection, graft loss, or death in 10 recipients after transplantation, and another 2 received nephrectomy due to dysfunction. Postoperative follow-up of the patients who received the pharmaceutical services from the clinical pharmacist showed an effectiveness in managing medicationrelated complications, patient-related factors, and an improvement of the outcomes. Conclusions:The three-step protocol of pharmaceutical services for pharmaceutical care and individual dosing regimen sponsored by pharmacists facilitated access to personalized therapies for children undergoing kidney transplantation in our hospital.

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“…Pharmacy Practice 2022 Jul-Sep;20(3):2708. https://doi.org/10.18549/PharmPract.2022.3.2708 2 hospitalized patients as well as reductions in hospital readmissions. [4][5][6][7][8][9] Disagreement between health care providers on medicationrelated problems or pharmaceutical interventions can lead to several adverse clinical outcomes, including; sub-optimal treatment, drug toxicities or increased overall healthcare cost. 10,11 A more recent study, showed poor overall agreement on the severity of clinical pharmacist interventions by other different health care providers in the team.…”

Section: Introductionmentioning

confidence: 99%

Levels of agreement among clinical pharmacists on the impact of pharmaceutical interventions in Oman: A retrospective analysis

Al-Maqbali¹,

Taqi²,

Al-Hamadani³

et al. 2022

PHARMPRACT

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Objectives: Disagreement between health care providers on medication-related interventions can affect clinical outcomes. We aimed to study the outcomes and significance of clinical pharmacists' interventions and evaluate the levels of agreement between different clinical pharmacists on the impact of pharmaceutical interventions. Methodology: A retrospective study was conducted at a tertiary care hospital in Oman. The study included all documented interventions by clinical pharmacists for all categories of admitted patients that met the inclusion criteria. Results: The originator clinical pharmacists interjected to improve the efficacy of treatment in (58%, n=1740) of the interventions, followed by toxicity reduction (24%). The level of agreement in the clinical significance resulted in substantial Scotts' kappa (k) between the originator and the first reviewer, the first and second reviewers, and the second reviewer and supervisor (86%; k=0.77; P<.001), (77%; k=0.63; P<.001), (84%; k=0.77; P<.001), respectively. In terms of grading of clinical significance, the originator clinical pharmacists recorded moderate significance in 50% of the interventions, followed by major (30%), not applicable (8.4%), and minor (7.3%). The level of agreement in the clinical significance resulted in substantial Scotts' k between the originator and the first reviewer, and between the second reviewer and supervisor (82%; k=0.72; P<.001), (84%; k=0.77; P<.001), respectively. The level of agreement between the first and second reviewer was fair (55%; k=0.28; p<0.001). Conclusion: Clinical pharmacists' interventions have a crucial impact on patient safety, improving efficacy and reducing toxicities. Overall, there was a substantial agreement among clinical pharmacists on the clinical significance and grading of the interventions..

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The impact of the clinical pharmacist-led interventions in China: A systematic review and Meta-Analysis

Cited by 18 publications

References 18 publications

Clinical Pharmacist’s Role in Optimizing Therapy through Drug-Related Problems Identification

Clinical Pharmacist’s Role in Optimizing Therapy through Drug-Related Problems Identification

Pharmaceutical services based on therapeutic care pathway for kidney transplantation from donors of infants and young children: a single-center experience

Levels of agreement among clinical pharmacists on the impact of pharmaceutical interventions in Oman: A retrospective analysis

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