Information management, an important element of which is the information system, has a direct impact on the functioning of a company, including its competitive position. Information management is related to the shape of the organizational culture, represented, inter alia, by the context of trust, relationship, and communication. The shape of the organizational culture, including the functioning of the information system, is particularly influenced by factors (usually external) that appear in a sudden and unpredictable manner. This impact increases with the intensity and scale of their influence. The recent COVID-19 pandemic should undoubtedly be considered such a factor. As a result, many enterprises suddenly had to switch to remote work. The aim of this paper is to analyze the essence and recognize the impact of the forced transition to a remote form of work on trust as a shaping and effective factor in the functioning of the company’s information system. To achieve this goal, the results of qualitative research conducted by the authors during the period March 2020–February 2021 and quantitative research conducted in February 2021 were used. In connection with the conducted research, it was found that trust is a very important factor influencing the efficiency and quality of employees’ work. It was also found that the forced need to switch to remote work mode was a problem for most people. This was influenced by both the time of the pandemic, as well as technical and organizational problems. As a result of observations, own experiences, interviews, and a questionnaire survey, the authors state that the necessity to switch from traditional to remote work resulted in an increase in the costs of functioning of people, including employees.