The Impact of the donor-recipient gender matching on the graft survival from live donors

Abstract

Background: Several factors like age of recipient, BMI, serum cratinnine , and positive history of dialysis are important in predicting graft survival in kidney transplant recipients. One factor that can affect transplant outcomes and is usually ignored is the gender of donor and recipients. Methods: A total of 1113 kidney transplant recipients were studied in a retrospective cohort study. Several factors were taken into account for graft survival and outcomes like gender and age of donor and recipients in addition to common recipient factors like cratinnine , eGFR, BMI, and positive history of dialysis. Results: The most successful transplant based on donor-recipient gender was seen in male donor to male recipient and then male donor to female recipient. In female transplant recipients, level of serum cratinnine , and eGFR, positive dialysis history before transplant, and low donor hemoglobin level can be good prognostic factors recommended to be considered for kidney transplant survival. Conclusions: Our results suggested that gender matching for kidney transplant. Only on some exceptional occasions, male donor to female recipient kidney transplant may be successful and female donors to male recipients are not suggested, especially in aged patients with history of dialysis.