The impact of the modification of the composition and the quantity of extemporaneous preparation on its price value

Abstract

Background: The aim of this study is the analysis and estimation of the impact of the modification of the composition of extemporaneous preparation dispensed by the community pharmacy on their price value. The modification of ointment base, dosage form, active ingredient and excipient concentration, prescribing two separate preparations instead of double quantity of extemporaneous preparation, prices of the ingredients and packaging have been evaluated. Material and method: 1407 prescriptions have been prescribed by 330 doctors providing their practice in 212 medical institutions. On the basis of these prescriptions five community pharmacies situated in Olsztyn, Elblag, Paslek and Ilawa in Warmian-Masurian Voivodeship made 1407 extemporaneous preparations in 2011. The information contained in prescriptions has become a foundation for creating a database using MS Excel tool. Statistical analysis and arithmetic mean have been applied. Results: The average price value of the extemporaneous preparations in the test material amounts to PLN 34.05. The price value of 90% of the extemporaneous preparations is within PLN 15.89 – PLN 50.00 . The price value of 10% is above PLN 50.00 including 1% over PLN 100.00. The modification of the ointment base has triggered, on average, a 38% increase of the price value, the modification of dosage form - 37%, prescribing two separate preparations instead of double quantity of the extemporaneous preparation - 32%, modification of active ingredient concentration - 23%, modification of excipient concentration - 14%. The purchase prices of ingredients and packaging have not been uniform.