The impact of the new coronavirus infection on the state of arterial bed in healthy individuals and patients with arterial hypertension

Abstract

Objective: to identify indicators of arterial stiffness that change after COronaVlrus Disease-2019 (COVID-19). Material and methods. Included were 112 people examined before and after the start of the new coronavirus infection (NCI) pandemic: healthy individuals (groups "H" and "H/COVID +") and patients with arterial hypertension (AH) (groups "AH" and "AH/COVID+"). An isolated comparative study was carried out in groups of healthy people and patients with hypertension. Results. Individuals in the "H/COVID+" group had higher levels of non-high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and more low values of high-density lipoprotein cholesterol (p=0.038; p=0.032; p=0.006) when compared with group "H". According to ABPM data, between the "AH" and "AH/Covid+" groups it was revealed difference at night level of reflected wave transit time (RWTT). An increase in cardio-ankle vascular index (L-/CAVI.,) in healthy persons and subjects with AH (p=0.001; p=0.004). In patients "H/COVID+" group higher values of pulse wave velocity in the aorta (PVW), elastic arteries type (R/L - PVW) and biological age (p=0.001; p=0.005; p=0.001) were registered. Conclusion. In healthy individuals who have had COVID-19, lipid profile abnormalities were noted, as well as an increase in L-/CAVI., when compared with the group of those who were not ill. In patients with AH after COVID-19, a negative change in the majority of indicators of arterial stiffness was noted.