The impact of the Polish mass breast cancer screening program on prognosis in the Pomeranian Province

Abstract

IntroductionMammographic screening results in diagnosis of less advanced breast cancer (BC). A meta-analysis of randomized clinical trials confirmed that BC screening reduces mortality. In 2007, the National Breast Cancer Screening Program (NBCSP) was established in Poland with the crucial aim of reducing mortality from BC. The purpose of this study was to assess the impact of participation in the NBCSP on prognosis.Material and methodsA single institution, non-randomized retrospective study was undertaken. The study population comprised 643 patients with BC treated in the Department of Surgical Oncology (DSO) at the Medical University of Gdansk over a 4-year period, from 01.01.2007 until 31.12.2010. Patients were divided into two groups: group A – patients who participated in the NBCSP (n = 238, 37.0%); and group B – patients who did not participate in the NBCSP (n = 405, 63.0%).ResultsStatistical analysis revealed that group A displayed a less advanced AJCC stage (more patients in AJCC stage I, p = 0.002), lower tumor diameter (more patients with pT1, p = 0.006, and pT < 15 mm, p = 0.008) and a lower incidence of metastases to axillary lymph nodes (more patients with pNO, p = 0.01). From 2009 to 2010 the NBCSP revealed a statistically significant benefit – significantly more patients in stage 0 + I (60.7% vs. 48.8%, p = 0.018) and with tumors pT < 15 mm (48.8% vs. 35.1%, p = 0.011) were observed in group A.ConclusionsThe study results revealed the beneficial impact of the NBCSP. Superior prognostic factors and favorable staging were observed in women who participated in the NBCSP.

Cognitive-Behavioral Coping, Illness Perception, and Family Adaptability in Oncological Patients with a Family History of Cancer

“…At the same time, adopting prosocial behaviors for social relationing and assertive action are closely connected to positive control beliefs and an adaptive emotional perception of the illness in the case of oncological patients with a family history of cancer. These findings complete the findings of research supporting the significant correlation between coping strategies and illness perception [22, 35–38], taking into consideration the family adaptability in the context of a family history of cancer.…”

The utility of Leventhal’s model in the analysis of the psycho-behavioral implications of familial cancer – a literature review

“…The findings of this analysis can be used to develop and implement personalized psycho-educational programs aimed at modifying maladaptive representations and negative emotional responses related to familial cancer, reducing the barriers and enhancing the perceived benefits, which would result in increased compliance with treatment and screening programs [ 52 , 53 ], and increasing the quality of individual, familial and social life.…”

Ultrastructure of gap junction and Cx43 expression in gastric cancer tissues of the patients

“…In China, with increasing incidence and mortality, cancer has become the leading cause of death and it was estimated that 4,292,000 new cancer cases and 2,814,000 cancer deaths would occur in 2015 in China [7]. Cancer is associated with many concerns and gastric cancer has an important place in the worldwide incidence of cancer and cancer-related deaths [8][9][10][11][12][13]. Gastric cancer is the fifth most common cancer and third leading cause of cancer-related death worldwide [14].…”