2009
DOI: 10.1902/jop.2009.080376
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The Impact of the Stone Age Diet on Gingival Conditions in the Absence of Oral Hygiene

Abstract: The experimental gingivitis protocol is not applicable if the diet (e.g., Stone Age) does not include refined sugars. Although plaque levels increased, BOP and PD decreased. Subgingival bacterial counts increased for several species not linked to periodontitis, whereas tongue bacterial samples decreased during the study period.

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Cited by 133 publications
(159 citation statements)
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“…This was also consistent with the observation by Baumgartner et al (2009), (20) who observed that the inflammatory status of the bleeding gingival tissues may actually influence the accumulation of plaque biofilm leading to the intensity of staining at the affected body sites. Since the toothpowder was applied directly, a probiotic effect upon the bioaccumulation is most likely since the application was localized and thus the observed reduction in the tooth staining overall among the toothpowder users.…”
Section: Discussionsupporting
confidence: 92%
“…This was also consistent with the observation by Baumgartner et al (2009), (20) who observed that the inflammatory status of the bleeding gingival tissues may actually influence the accumulation of plaque biofilm leading to the intensity of staining at the affected body sites. Since the toothpowder was applied directly, a probiotic effect upon the bioaccumulation is most likely since the application was localized and thus the observed reduction in the tooth staining overall among the toothpowder users.…”
Section: Discussionsupporting
confidence: 92%
“…The human oral microbiota used to be substantially more diverse, but with the agricultural and industrial revolutions it underwent two major ecosystem shifts introducing the microbes associated with periodontal disease and caries respectively, with flour and sugar implicated in these shifts (47). An inappropriate innate immune response to these microbial changes is believed to underlie periodontitis, and may also exacerbate atherosclerosis (48,49), while limiting the sources of processed carbohydrate in diet can produce marked improvements in periodontal health (50,51). The small intestinal microbiota is proximal to both the satiety-sensing vagal afferents believed to play a key role in energy-homeostasis(52) (35), and to the immune system hub of the gut-associated lymphoid tissue (53,54).…”
Section: Microbes As Sensors Of Dietary Refinement -Dental and Systemmentioning
confidence: 99%
“…However, there is emerging evidence in humans that refined sugars drive periodontal inflammation 3 and calorie restriction by reverting to a 'hunter-gatherer' diet/lifestyle may substantially reduce gum inflammation. 4 Mechanisms likely involve meal-induced inflammation from refined sugar and/or saturated fat, mediated via oxidative stress pathways. 5 Periodontitis therefore likely contributes to elevated ACVD risk through co-morbidity due to an elevated systemic inflammatory burden.…”
Section: Periodontal Disease and Systemic Diseasementioning
confidence: 99%