2021
DOI: 10.1002/pds.5395
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The impact of tightened prescribing restrictions on proton pump inhibitor use in Australia: An evaluation using interrupted time series analysis

Abstract: Aim: In May 2019, Australia's Pharmaceutical Benefits Scheme (PBS) tightened the prescribing restrictions for publicly subsidized high and standard strength protonpump inhibitors (PPIs). We aimed to determine the impacts on PPI use in Australia.Methods: Population-based interrupted time series analysis of PBS dispensing claims for a 10% sample of PBS-eligible Australian residents from January 2017 to December 2020 and national prescription and over-the-counter sales to pharmacies from January 2017 to October 2… Show more

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“…Our pathway for evidence generation expands on a multi-stage approach that was demonstrated to be effective in foundational work preceding the establishment of MI-CRE [47][48][49]. In our experience, the particular questions posed by medicines policy agencies can be addressed simply through preliminary or descriptive exposure-endpoint feasibility analyses.…”
Section: Mi-cre Governance Modelmentioning
confidence: 99%
“…Our pathway for evidence generation expands on a multi-stage approach that was demonstrated to be effective in foundational work preceding the establishment of MI-CRE [47][48][49]. In our experience, the particular questions posed by medicines policy agencies can be addressed simply through preliminary or descriptive exposure-endpoint feasibility analyses.…”
Section: Mi-cre Governance Modelmentioning
confidence: 99%