The impact of urinary incontinence on health-related quality of life (HRQoL) in a real-world population of women aged 45-60 years: results from a survey in France, Germany, the UK and the USA

Abrams, Paul; Smith, Andrew Paul; Cotterill, Nikki

doi:10.1111/bju.12852

Cited by 109 publications

(113 citation statements)

References 16 publications

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“…Likewise, the ICIQ‐LUTSqol revealed good discriminant validity, with “effect on physical activities” demonstrating the highest discriminative power for distinguishing SUI cases from healthy controls. This is not surprising since it has been shown that patients who suffer from this condition are affected in various aspects of their everyday life . Additionally, the ICIQ‐LUTSqol showed excellent internal consistency and test–retest reliability, similar to results in China and Sweden (Supplement Table SII).…”

Section: Discussionsupporting

confidence: 64%

Validity, reliability, and responsiveness of the ICIQ‐UI SF and ICIQ‐LUTSqol in the Malaysian population

Lim

Liong

Lau

et al. 2015

Neurourology and Urodynamics

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Section: Discussionsupporting

confidence: 64%

Validity, reliability, and responsiveness of the ICIQ‐UI SF and ICIQ‐LUTSqol in the Malaysian population

Lim

Liong

Lau

et al. 2015

Neurourology and Urodynamics

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“…This is consistent with previous findings showing improvement in generic and disease-specific quality of life in the short, medium and long term after treatment of faecal incontinence [28]. A similar relationship has been seen between the ICIQ-UI-SF score and generic quality of life [33]. Our study supports the relationship between improved symptoms and quality of life.…”

Section: Discussionsupporting

confidence: 93%

Sacral neuromodulation for combined faecal and urinary incontinence following obstetric anal sphincter injury

et al. 2018

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Aim The aim of this study was to investigate the efficacy of sacral neuromodulation (SNM) in the treatment of faecal incontinence and concomitant urinary incontinence in women with a history of obstetric anal sphincter injury (OASIS).Method In this prospective study, consecutive women with faecal incontinence following OASIS accepted for SNM were screened for concomitant urinary incontinence. The primary outcome was the change in urinary incontinence score on the International Consultation on Incontinence Questionnaire for Urinary Incontinence, Short Form (ICIQ-UI-SF), between baseline and 12 months. Secondary outcomes included the change in St Mark's score, sexual function and quality of life, change in grade of urinary incontinence and disappearance of urgency.Results From March 2012 to September 2014, 39 women with combined faecal incontinence and urinary incontinence received SNM. Thirty-seven women were available for analysis after 12 months. The mean reduction in the ICIQ-UI-SF score between the baseline and 12 months was 5.8 (95% CI 3.7-8.0, P < 0.001). ICIQ-UI-SF was reduced in 29 (78%) women, urinary incontinence resolved in 13/37 (35%, 95% CI 20%-50%) patients, and urgency disappeared in 14/33 (42%, 95% CI 26%-59%). The mean reduction in the St Mark's score was 10.6 (95% CI 8.6-12.7, P < 0.001). Disease-specific quality of life, Euroqual 5-dimension visual analogue scale (EQ-5D VAS) and several areas of sexual function changed significantly for the better.Conclusion More than three-quarters of the women with combined faecal and urinary incontinence following OASIS reported a successful outcome with reduction in ICIQ-UI-SF at 12 months after SNM.Keywords Faecal incontinence, urinary incontinence, pelvic floor disorders/dysfunction, obstetric anal sphincter injury, sacral neuromodulation What does this paper add to the literature? A high prevalence of concomitant urinary incontinence was found in a selected group of women with faecal incontinence following obstetric anal sphincter injury treated with sacral neuromodulation. Faecal incontinence and concomitant urinary incontinence were treated successfully in the majority of women.

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“…In this cohort of women who were not seeking care for UI, 28 (67%) used protective products, primarily menstrual pads, for urine leakage, and 35 (95%) women reported score of 3 or higher (worse urinary-specific quality of life) on the ICIQ-UI SF. 26 Based on a cut off score of 67 on the ABC scale, 18 women (48%) were at high risk for future fall. Only 2 (5%) women were taking sedating medications (narcotics, benzodiazepines, over the counter sleep aids, anti-histamines) known to increase fall risk.…”

Section: Resultsmentioning

confidence: 99%

Noctural Enuresis as a Risk Factor for Falls in Older Community Dwelling Women with Urinary Incontinence

et al. 2016

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Purpose-To determine the association between urinary symptoms, fall risk and physical limitations in older community-dwelling women with urinary incontinence (UI).Materials and Methods-In-depth assessment of day and nighttime urinary symptoms, fall risk, physical function, physical performance tests and mental function in older communitydwelling women with UI and who had not sought care for their urinary symptoms. All assessments were performed in the participants' homes. We used univariable and multivariable linear regression to examine the relationship of urinary symptoms with fall risk, physical function, and physical performance.Results-In 37 women with UI (mean age 74 ± 8.4 years), 48% were at high risk for falls. Nocturnal enuresis was reported by 50%. Increased fall risk was associated with increasing frequency of nocturnal enuresis (p=0.04), worse lower limb (p<0.001) and worse upper limb (p<0.0001) function and worse performance on a composite physical performance test of strength, gait and balance (p=0.02). Women with nocturnal enuresis had significantly lower median physical performance test scores (7, range 0, 11) than women without nocturnal enuresis (median 9, range 1, 12, p=0.04). In a multivariable regression model that included age, nocturnal enuresis episodes and physical function, only physical function was associated with increased fall risk (p<0.0001).Conclusion-Nocturnal enuresis is common in older community-dwelling women with UI and may serve as a marker for fall risk even in women not seeking care for their urinary symptoms.

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The impact of urinary incontinence on health-related quality of life (HRQoL) in a real-world population of women aged 45-60 years: results from a survey in France, Germany, the UK and the USA

Abstract: ObjectiveTo develop a clear understanding of the relationship between severity of urinary incontinence (UI) and health-related quality of life (HRQoL) and mental well-being in a population of women of working age with the requisite demands of a busy, active life.

Cited by 109 publications

References 16 publications

Validity, reliability, and responsiveness of the ICIQ‐UI SF and ICIQ‐LUTSqol in the Malaysian population

Validity, reliability, and responsiveness of the ICIQ‐UI SF and ICIQ‐LUTSqol in the Malaysian population

Sacral neuromodulation for combined faecal and urinary incontinence following obstetric anal sphincter injury

Noctural Enuresis as a Risk Factor for Falls in Older Community Dwelling Women with Urinary Incontinence

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