2024
DOI: 10.1007/s00213-024-06705-7
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The impact of voluntary wheel-running exercise on hippocampal neurogenesis and behaviours in response to nicotine cessation in rats

Magdalena Zaniewska,
Sabina Brygider,
Iwona Majcher-Maślanka
et al.

Abstract: Rationale The literature indicates that nicotine exposure or its discontinuation impair adult hippocampal neurogenesis in rats, though the impact of exercise on this process remains unclear. We have previously shown that disturbances in the number of doublecortin (DCX, a marker of immature neurons)-positive (DCX+) cells in the dentate gyrus (DG) of the hippocampus during nicotine deprivation may contribute to a depression-like state in rats. Objectives Thi… Show more

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