The Impact Triad (Severity, Importance, Self-management) as a Method of Enhancing Measurement of Personal Life Impact of Rheumatic Diseases

Sanderson, Tessa; Hewlett, Sarah; Flurey, Caroline; Dures, Emma; Richards, Pamela; Kirwan, John R.

doi:10.3899/jrheum.100700

Cited by 38 publications

(32 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is consistent with the proposal that patients experience the impact of their condition, an interaction between severity of the disease, their personal circumstances and their ability to cope with the condition, and are less directly aware of specific pathological changes. [22] Patients struggled with attribution of signs and symptoms to either the disease or influential factors such as aging or side effects of medication. Many PROs assume patients are able to differentiate between for example pain due to RA and pain due to flu, and there is some evidence that this may well be the case.…”

Section: Discussionmentioning

confidence: 99%

The patient perspective on remission in rheumatoid arthritis: ‘You've got limits, but you're back to being you again’

et al. 2014

Self Cite

View full text Add to dashboard Cite

ObjectivesThe aim of rheumatoid arthritis (RA) treatment is remission. As treatment should be targeted at outcomes relevant to patients, it is important to understand how patients perceive remission, and to assess whether the current definition of remission adequately reflects these perceptions. The objective of this study is to explore the patient perspective on remission in RA.MethodsNine focus-group discussions in Austria, The Netherlands and UK were conducted, including patients in American College of Rheumatology (ACR)/ European League of Rheumatology (EULAR) remission, self-declared remission and in moderate/high disease activity. Moderators employed a prespecified interview guide helped to engage patients in a discussion on their experience with remission. Inductive thematic analysis was performed within each country, and identified themes were discussed across countries.Results47 RA patients (66% women, disease duration 9 years) participated. Three major themes of patient-perceived remission emerged: (1) symptoms would either be absent or strongly reduced, (2) impact of the disease on daily life would diminish by increased independence, ability to do valued activities, improved mood and ability to cope; (3) leading to a return to normality, including work, family role and perception of others. Patients felt the concept of remission was influenced by ageing, side effects of medication, comorbidities, accrued damage to joints and disease duration. Opinions on duration of state, the role of medication and measurement instruments varied widely.ConclusionsPatients characterise remission by the absence or reduction of symptoms, but more directly by decreased daily impact of their condition and the feeling of a return to normality. The next step is to study whether an additional patient-perceived measure of remission may add value to the ACR/EULAR definition of remission.

show abstract

Section: Discussionmentioning

confidence: 99%

The patient perspective on remission in rheumatoid arthritis: ‘You've got limits, but you're back to being you again’

et al. 2014

Self Cite

View full text Add to dashboard Cite

show abstract

“…New PROs should be continuously developed to guarantee that truly relevant domains are covered in a cross-culturally valid way. Instruments such as the Personal Life Impact Measurement Scales seem especially promising [174,175]. Studies addressing the influence of psychological variables on response to medication in randomized controlled trials are urgently needed, as are new efforts and training to foster our understanding of coping strategies, by focusing on longitudinal and within-person research designs (eg, daily diary studies).…”

Section: Future Researchmentioning

confidence: 99%

Psychological Factors Associated with Response to Treatment in Rheumatoid Arthritis

Santiago

Geenen²,

J.W.G.³

et al. 2014

CPD

View full text Add to dashboard Cite

This paper presents a comprehensive review of research relating psychological domains with response to therapy in patients with rheumatoid arthritis. A holistic approach to the disease was adopted by incorporating not only disease activity but also dimensions of the impact of disease on patients' lives. Psychological distress, including depression and anxiety, is common among patients with rheumatoid arthritis and has a significant negative impact on response to therapy and on patients' abilities to cope with chronic illness. Evidence regarding the influence of positive psychological dimensions such as acceptance, optimism, and adaptive coping strategies is scarce. The mechanisms involved in these interactions are incompletely understood, although changes in neuro-endocrine-immune pathways, which are common to depression and rheumatoid arthritis, seem to play a central role. Indirect psychological influences on therapeutic efficacy and long-term effectiveness include a myriad of factors such as adherence, placebo effects, cognition, coping strategies, and family and social support. Data suggest that recognition and appropriate management of psychological distress may improve response to treatment and significantly reduce disease burden.

show abstract

“…More recently, researchers from Bristol have suggested that the impact of a disease or its components is dependent on three interdependent concepts: severity, importance and self-management 4. Severity and importance are relatively well-known components that have already been incorporated in so-called “personal preference” tools such as the McMaster-Toronto Arthritis (MACTAR) scale that asks patients to rank their five most important activities and subsequently tracks changes in the ability to perform these activities over time 5.…”

mentioning

confidence: 99%

RAID: a valid tool to quantify the impact of rheumatoid arthritis. But what impact will it have on the core set for trials?

Boers

2011

Ann Rheum Dis

View full text Add to dashboard Cite

The Impact Triad (Severity, Importance, Self-management) as a Method of Enhancing Measurement of Personal Life Impact of Rheumatic Diseases

Cited by 38 publications

References 12 publications

The patient perspective on remission in rheumatoid arthritis: ‘You've got limits, but you're back to being you again’

The patient perspective on remission in rheumatoid arthritis: ‘You've got limits, but you're back to being you again’

Psychological Factors Associated with Response to Treatment in Rheumatoid Arthritis

RAID: a valid tool to quantify the impact of rheumatoid arthritis. But what impact will it have on the core set for trials?

Contact Info

Product

Resources

About