PurposeThis paper addresses the under-explored collateral damage of economic sanctions, shedding light on the disproportionate harm endured by the most vulnerable segments of societies, which at the same time lack political influence to effect the ruling government into change. The primary objective is to review the literature on humanitarian repercussions associated with sanctions, concluding if they really are a comparably human way of international interference.Design/methodology/approachEmploying a systematic literature review, adhering to the PRISMA approach, and incorporating key term definitions and clear selection criteria, this review analyses 52 studies sourced from Scopus and EconBiz.FindingsThe surveyed literature reveals profound adverse impacts of sanctions on health, economic well-being, inequality, and education. Critical gaps in the literature such as disproportional focus on extreme cases like Iran and Iraq, scarce literature on effects on education and inequality, and predominantly inadequate control groups are identified, limiting the generalizability of existing findings.Originality/valueThis paper is the first systematic and replicable review of the literature on the effects of sanctions using a capabilistic approach to define poverty. Highlighting gaps in the current research landscape underscores the limited generalizability of reviewed results. Providing a well-structured summary of existing literature, this work serves as a foundation for future research.