The impacts of parity on lung function data (LFD) of healthy females aged 40 years and more issued from an upper middle income country (Algeria): A comparative study

Abstract

BackgroundStudies evaluating the impacts of parity on LFD of healthy females presented controversial conclusions.AimTo compare the LFD of healthy females broken down according to their parities.MethodsA medical questionnaire was administered and anthropometric data were determined. Two groups [G1 (n = 34): ≤ 6; G2 (n = 32): > 6] and three classes [C1 (n = 15): 1–4; C2 (n = 28): 5–8; C3 (n = 23): 9–14] of parities were identified. LFD (plethysmography, specific airway resistance (sRaw)] were determined. Student’s t-test and ANOVA test with post-Hoc test were used to compare the two groups’ and the three classes’ data.ResultsG1 and G2 were age and height matched; however, compared to G1, G2 had a lower body mass index (BMI). C1, C2 and C3 were height, weight and BMI matched; however, compared to C2, C3 was older. G1 and G2 had similar values of FEV1, forced- and slow- vital capacities (FVC, SVC), maximal mid-expiratory flow (MMEF), forced expiratory flow at x% of FVC (FEFx%), peak expiratory flow (PEF), expiratory and inspiratory reserve volumes (ERV, IRV, respectively), inspiratory capacity (IC), sRaw, FEV1/FVC, FEV1/SVC, and residual volume/total lung capacity (RV/TLC). The three classes had similar values of MMEF, FEFx%, PEF, thoracic gas volume (TGV), ERV, IRV, FEV1/FVC, FEV1/SVC and RV/TLC. Compared to G1, G2 had higher TGV (2.68±0.43 vs. 3.00±0.47 L), RV (1.80±0.29 vs. 2.04±0.33 L) and TLC (4.77±0.62 vs. 5.11±0.67 L). Compared to C1, C2 had higher FEV1 (2.14±0.56 vs. 2.47±0.33 L), FVC (2.72±0.65 vs. 3.19±0.41 L), SVC (2.74±0.61 vs. 3.24±0.41 L), TLC (4.47±0.59 vs. 5.10±0.58 L), IC (1.92±0.41 vs. 2.34±0.39 L) and sRaw (4.70±1.32 vs. 5.75±1.18 kPa*s). Compared to C1, C3 had higher TLC (4.47±0.59 vs. 5.05±0.68 L) and RV (1.75±0.29 vs. 2.04±0.30 L).ConclusionIncreasing parity induced a tendency towards lung-hyperinflation.

Sex differences in pulmonary function parameters among Indigenous Australians with and without chronic airway disease

“…Due to these underlying sex differences, it is plausible that the effects of disease on PFTPs will also differ. These differences may also be related to other internal or external factors as previously documented in the published literature [2][3][4][5][6][7][8][9][10][26][27][28][29]. However, it was beyond the scope of this current study to explore other potential factors contributing to sex differences in PFTPs in our study patients.…”

The global lung function initiative 2021 (GLI-2021) norms provide mixed results for static lung volumes (SLVs) in Algerian adults

“…This point was clearly foreseen by the GLI Task Force noting that the derived GLI-2021 norms may not be appropriate for individuals of ‘non-European’ ancestry [ 7 ]. The second explanation is related to the effects of parity on SLVs [ 4 , 14 ]. A previous Algerian study [ 14 ] reported that compared to females with a parity ≤ 6, those with a parity > 6 had higher FRC and RV.…”

“…The second part [ 12 ] aimed at testing the validity of the Eastern Algeria plethysmographic norms [ 11 ]. The third part [ 14 ] aimed at evaluating the impact of parity on females’ plethysmographic data. The fourth part constitutes the topic of this study.…”

“…Participants were selected by convenience sampling from the acquaintances of patients hospitalized at the above department during, for example, the hospital visiting time. The inclusion, non-inclusion, and exclusion criteria, which were previously described [ 10 , 12 , 14 ], are reported in Figure 2 . In this study, only healthy adults aged ≥18 years with technically acceptable and repeatable plethysmographic/spirometric maneuvers were included.…”

“…One qualified person ( AK in the authors’ list) performed all the plethysmographic/spiromtric tests in the morning. All measurements were performed with a body plethysmograph (Body-box 5500, MediSoft, Belgium), following carefully the international guidelines [ 8 , 10–12 , 14 , 17 , 18 ] in the following order: FRC maneuver and spirometry maneuver. The spirometer was calibrated daily with a 3-L syringe.…”