The Implementation of Fluorescence‐Based Detection in LTCC (Low‐Temperature‐Co‐Fired‐Ceramics) Microfluidic Modules

Malecha, Karol

doi:10.1111/ijac.12416

Cited by 14 publications

(6 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Prepared GQDs were highly luminescent due to the aromatic planar structure. The ceramic-based miniature biosensor was designed and constructed through the immobilization of laccase on an electrochemically synthesized polymer-poly(bis(4-(thiophen-2-yl)phenyl)diphenylsilane), based on low temperature co-fired ceramics technology (LTCC), prepared as presented by K. Malecha [ 107 ]. This sensing system utilized the catalytic oxidation of DA to dopamine-o-quinone (DOQ), and then to poly(DA) (in alkaline conditions), which can selectively quench the strong luminescence of GQDs due to Förster Resonance Energy Transfer (FRET).…”

Section: Application In Different Fieldsmentioning

confidence: 99%

Conducting Silicone-Based Polymers and Their Application

et al. 2021

View full text Add to dashboard Cite

Over the past two decades, both fundamental and applied research in conducting polymers have grown rapidly. Conducting polymers (CPs) are unique due to their ease of synthesis, environmental stability, and simple doping/dedoping chemistry. Electrically conductive silicone polymers are the current state-of-the-art for, e.g., optoelectronic materials. The combination of inorganic elements and organic polymers leads to a highly electrically conductive composite with improved thermal stability. Silicone-based materials have a set of extremely interesting properties, i.e., very low surface energy, excellent gas and moisture permeability, good heat stability, low-temperature flexibility, and biocompatibility. The most effective parameters constructing the physical properties of CPs are conjugation length, degree of crystallinity, and intra- and inter-chain interactions. Conducting polymers, owing to their ease of synthesis, remarkable environmental stability, and high conductivity in the doped form, have remained thoroughly studied due to their varied applications in fields like biological activity, drug release systems, rechargeable batteries, and sensors. For this reason, this review provides an overview of organosilicon polymers that have been reported over the past two decades.

show abstract

Section: Application In Different Fieldsmentioning

confidence: 99%

Conducting Silicone-Based Polymers and Their Application

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The final LTCC laminate was cofired in the air using a standard thermal profile (T max = 850 • C). A detailed description of the LTCC-based microsystem fabrication process can be found in [33]. After cofiring, a PMMA optical fiber with a diameter of 1 mm and NA = 0.5 was placed inside the channel and glued.…”

Section: Microsystem Technologymentioning

confidence: 99%

Fluorescence Sensing Platforms for Epinephrine Detection Based on Low Temperature Cofired Ceramics

Baluta

Malecha

Świst

et al. 2020

Sensors

Self Cite

View full text Add to dashboard Cite

A novel fluorescence-sensing pathway for epinephrine (EP) detection was investigated. The ceramic-based miniature biosensor was developed through the immobilization of an enzyme (laccase, tyrosinase) on a polymer—poly-(2,6-di([2,2′-bithiophen]-5-yl)-4-(5-hexylthiophen-2-yl)pyridine), based on low temperature cofired ceramics technology (LTCC). The detection procedure was based on the oxidation of the substrate, i.e., in the presence of the enzyme. An alternative enzyme-free system utilized the formation of a colorful complex between Fe2+ ions and epinephrine molecules. With the optimized conditions, the analytical performance illustrated high sensitivity and selectivity in a broad linear range with a detection limit of 0.14–2.10 nM. Moreover, the strategy was successfully used for an EP injection test with labeled pharmacological samples.

show abstract

“…A very promising alternative for construction of new micro-devices is LTCC (Low Temperature Co-fired Ceramic [ 93 ]) technology, consisting in the creation of three-dimensional structures of electronic systems based on pressed and co-poured ceramic foils with printed functional layers [ 94 , 95 ]. This method was used by Baluta et al They proposed a convenient fluorescence dopamine-sensing strategy based on polydopamine formed on the surface of graphene quantum dots (GQDs).…”

Section: Applications Of Qds-based Sensorsmentioning

confidence: 99%

Optical Sensors Based on II-VI Quantum Dots

et al. 2019

Self Cite

View full text Add to dashboard Cite

Fundamentals of quantum dots (QDs) sensing phenomena show the predominance of these fluorophores over standard organic dyes, mainly because of their unique optical properties such as sharp and tunable emission spectra, high emission quantum yield and broad absorption. Moreover, they also indicate no photo bleaching and can be also grown as no blinking emitters. Due to these properties, QDs may be used e.g., for multiplex testing of the analyte by simultaneously detecting multiple or very weak signals. Physico-chemical mechanisms used for analyte detection, like analyte stimulated QDs aggregation, nonradiative Förster resonance energy transfer (FRET) exhibit a number of QDs, which can be applied in sensors. Quantum dots-based sensors find use in the detection of ions, organic compounds (e.g., proteins, sugars, volatile substances) as well as bacteria and viruses.

show abstract

The Implementation of Fluorescence‐Based Detection in LTCC (Low‐Temperature‐Co‐Fired‐Ceramics) Microfluidic Modules

Cited by 14 publications

References 33 publications

Conducting Silicone-Based Polymers and Their Application

Conducting Silicone-Based Polymers and Their Application

Fluorescence Sensing Platforms for Epinephrine Detection Based on Low Temperature Cofired Ceramics

Optical Sensors Based on II-VI Quantum Dots

Contact Info

Product

Resources

About