Red rice (O. sativa) is one the most prevalent and damaging weed problems in direct seeding rice systems worldwide and can cause significant losses in rice productivity and quality. Red rice has been a problem in the United States for decades, and it is a growing problem in Asia, where 90 percent of the global rice production occurs. Unlike for other crops, where genetically engineered (GE) herbicide tolerant varieties are available, to date, Clearfield (CL) and Provisia rice are the only technologies available to selectively control red rice using chemical herbicides in commercial rice fields. We develop a counterfactual scenario without CL rice and ascertain the yield and quality losses due to red rice infestation in the Mid-South of the United States. Our findings suggest that even with the higher costs of CL rice, relative to non-CL rice, that the returns are $0.15, $0.36, and $0.54 more for every dollar invested than non-CL rice with a light, moderate, and heavy initial red rice infestation rate, respectively. These results imply that the higher upfront costs for CL rice are offset by more than proportional higher profits relative to their non-CL rice counterparts.