The importance of accurate instrumentation for electrical bioimpedance measurements

Abstract

Bioimpedance analysis (BIA) has been successfully used for cancer diagnosis and biomaterial characterizations due to its safety, low cost, effectiveness, portability and applicability. The correct diagnosis depends on the quality of measured data which, in turns, depends on the bioinstrumentation used for capturing and processing the signals.With the advent of innovative materials and integrated circuits, novel approaches in bioinstrumentation have been used to increase both accuracy and precision, and then obtaining a better diagnosis. However, tiny electrodes used to register the signal, such as biosensors, and the increasing number of channels of such a system, impose a great limitation in the electronic, especially at higher frequencies. Further researches in electrical bioimpedance are highly recommended for working with novel and advanced clinical applications in biology and medicine.