2022
DOI: 10.1080/10408398.2022.2087595
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The importance of AMPK in obesity and chronic diseases and the relationship of AMPK with nutrition: a literature review

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Cited by 13 publications
(7 citation statements)
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“…Based on the results of the present study, alteration of AMPK mRNA levels in visceral adipose tissue could be involved in ameliorating T2DM following exercise adaptations. AMPK is involved in carbohydrate and fat metabolism, insulin signaling, and inflammation which are reduced in obesity 37 . Villena et al reported increased body weight and adipose tissue mass in AMPK knockout mice which supports our results 38 .…”
Section: Discussionmentioning
confidence: 99%
“…Based on the results of the present study, alteration of AMPK mRNA levels in visceral adipose tissue could be involved in ameliorating T2DM following exercise adaptations. AMPK is involved in carbohydrate and fat metabolism, insulin signaling, and inflammation which are reduced in obesity 37 . Villena et al reported increased body weight and adipose tissue mass in AMPK knockout mice which supports our results 38 .…”
Section: Discussionmentioning
confidence: 99%
“…AMP-activated protein kinase (AMPK), a key cellular energy sensing complex [ 10 , 11 ], has emerged as a mediator between the misalignment of circadian rhythms and metabolic homeostasis [ 12 , 13 ]. Activation of AMPK has been associated with beneficial effects on metabolism, such as improving insulin sensitivity and ameliorating obesity [ 14 , 15 ]. Interestingly, melatonin has been reported to activate AMPK, providing a potential mechanistic link between melatonin and improved cardiometabolic outcomes [ 16 , 17 ].…”
Section: Introductionmentioning
confidence: 99%
“…2 of 13 AMP-activated protein kinase (AMPK), a key cellular energy sensing complex [10,11], has emerged as a mediator between the misalignment of circadian rhythms and metabolic homeostasis [12,13]. Activation of AMPK has been associated with beneficial effects on metabolism, such as improving insulin sensitivity and ameliorating obesity [14,15]. Interestingly, melatonin has been reported to activate AMPK, providing a potential mechanistic link between melatonin and improved cardiometabolic outcomes [16,17].…”
Section: Introductionmentioning
confidence: 99%