The importance of cortical bone orthotropicity, maximum stiffness direction and thickness on the reliability of mandible numerical models

Apicella, Davide; Aversa, Raffaella; Ferro, Fabrizia; Ianniello, Domenico; Apicella, Antonio

doi:10.1002/jbm.b.31569

Cited by 34 publications

(75 citation statements)

References 29 publications

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“…This continuously improving the "in silico" human synthetic calculation capability shortens the decisional time for the evaluation of the robustness of a design idea (Apicella et al, 2010;Aversa et al, 2009;2016a;206b;2016c;Sorrentino et al, 2009;Syed et al, 2016).…”

Section: Mimicking Mechanism Of the Natural Evolution Where A Biologmentioning

confidence: 99%

“…4) and highly non-linear biofidel modeling of bone mechanical modeling, in silico, in vitro and in vivo tests (Fig. 5) (Aversa et al, 2009;Apicella et al, 2010). (Gramanzini et al, 2016) If an implant fractures due to inadequate strength or mismatch in mechanical property between the bone and implant, then this is referred to as biomechanical incompatibility.…”

Section: An Evolutionary Design Biomedical Case Study: Biomechanics Amentioning

confidence: 99%

“…Thus, a customized material with excellent combination of high strength and stiffness matching that of the bone has to be used for biomechanical integrated implantation to avoid loosening of implants and higher service period to avoid revision surgery (Apicella et al, 2010;Aversa et al, 2016a;2016b;2016c).…”

Section: An Evolutionary Design Biomedical Case Study: Biomechanics Amentioning

confidence: 99%

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Biomimetic and Evolutionary Design Driven Innovation in Sustainable Products Development

Aversa¹,

Petrescu²,

Petrescu³

et al. 2016

American Journal of Engineering and Applied Sciences

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An innovative, design-driven, sustainable approach in conceiving, developing, producing, using new materials can be effective in strengthening the competiveness and success of creative industries linked to manufacturing (e.g., biomedical, architecture, automotive, art, crafts, supports for cultural items, decoration, fashion, furniture, lighting, interior design materials and products, jewels, luxury, media supports, publishing, sport and toys), adding value to products and processes also by 'immaterial' factors (e.g., trend translation, enhanced sensations, values). The vision that the research and the advancement of scientific and technological knowledge can be driven by the needs of sustainable development of products and goods has been revived as a strategy for sustainable development. In the evolutionary Design process, creativity determines the mutation of an object shape (material or structure morphology) and this triggers an evolutionary design that repeatedly involves technological development of material, shape and structure. A Biomedical product evolutionary design case study based on these principles has been specifically addressed to the dissemination and spreading of innovative material and technology greener solutions. The use of the evolutionary design in the creative medical industry sectors, while adopting sustainable and socially responsible approach to reduce energy consumption and environmental impact conveys a holistic view of the industrial design process in the field of biomedical application.

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Section: Mimicking Mechanism Of the Natural Evolution Where A Biologmentioning

confidence: 99%

Section: An Evolutionary Design Biomedical Case Study: Biomechanics Amentioning

confidence: 99%

Section: An Evolutionary Design Biomedical Case Study: Biomechanics Amentioning

confidence: 99%

See 1 more Smart Citation

Biomimetic and Evolutionary Design Driven Innovation in Sustainable Products Development

Aversa¹,

Petrescu²,

Petrescu³

et al. 2016

American Journal of Engineering and Applied Sciences

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“…Studies on prostheses biomimetics involving these innovative fabrication processes (Annunziata et al, 2006;Apicella et al, 2010;Aversa et al, 2009; have opened to the definition of new design criteria for more biomechanically compatible prostheses production. Figure 1 illustrates the biomimetic approach using in silico, in vitro and in vivo validation steps for biofidel bone modeling.…”

Section: Introductionmentioning

confidence: 99%

“…Finite Element Models have been presented in previous works where the influence of the morphology of femur and mandible structureshas been evaluated (Aversa et al, 2016(Aversa et al, , 2009Apicella et al, 2010;Beaupre and Hayes, 1985;Reilly and Burstein, 1974;1975).…”

Section: Introductionmentioning

confidence: 99%

Flexible Stem Trabecular Prostheses

Aversa¹,

Petrescu²,

Petrescu³

et al. 2016

American Journal of Engineering and Applied Sciences

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Abstract:The complex biomechanics and morphology of the femur proximal epiphysis are presented. This specific region in human femur is characterized by a high flexibility compared to that of other primates, since evolved lighter and longer due to the human verticalposition and more balanced loading. The nature and fine morphology of the femur head and its structural behavior have been investigated. Isotropic and orthotropic trabecular structures, which are not present in other primates, have been associated to compression and tensioned areas of the femur head.These isotropic/orthotropic trabecularmorphologies and allocationsgovern the stress and strains distribution in the overall proximal femur region. Useof femur proper biofidel modeling while enabling the explanationof physiological stress distribution elucidates the critical mechanical role of the trabecular bone that should be accounted in the design new innovative more "biologic" prosthetic system.

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